Maia Stanisławska-Kubiak, Katarzyna Anna Majewska, Agata Krasińska, Paulina Wais, Dominik Majewski, Ewa Mojs, Andrzej Kȩdzia
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Scopus, PubMed, and Web of Science databases were searched for relevant literature using selected keywords. The results were summarized using a narrative synthesis. Disturbances in glucose metabolism during childhood may have a lasting negative effect on the development of the brain and related cognitive functions. To optimize intellectual development in children with diabetes, it is essential to prevent disorders of the central nervous system by maintaining peri-normal glycemic levels. Based on the performed literature review, it seems necessary to take additional actions, including repeated neuropsychological evaluation with early detection of any cognitive dysfunctions, followed by the development of individual management strategies and the training of appropriate skills, together with complex, multidirectional environmental support.</p>","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10981223/pdf/","citationCount":"0","resultStr":"{\"title\":\"Brain functional and structural changes in diabetic children. 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引用次数: 0
摘要
1 型糖尿病(T1D)患者的神经心理功能对治疗效果至关重要,而治疗的复杂性需要大量的知识、关注和投入。智力上的限制使其很难达到最佳的代谢平衡,而缺乏这种平衡会导致认知功能进一步恶化。本研究旨在对糖尿病对儿童期大脑结构和功能的影响的现有知识进行叙述性回顾,并提出优化 T1D 儿童智力发育的可能措施。我们使用选定的关键词在 Scopus、PubMed 和 Web of Science 数据库中搜索了相关文献。研究结果采用叙事综合法进行总结。儿童时期葡萄糖代谢紊乱可能会对大脑发育和相关认知功能产生持久的负面影响。为了优化儿童糖尿病患者的智力发育,必须通过维持近正常血糖水平来预防中枢神经系统紊乱。根据已完成的文献综述,似乎有必要采取额外的行动,包括反复进行神经心理学评估,及早发现任何认知功能障碍,然后制定个人管理策略,进行适当的技能培训,同时提供复杂的、多方位的环境支持。
Brain functional and structural changes in diabetic children. How can intellectual development be optimized in type 1 diabetes?
The neuropsychological functioning of people with type 1 diabetes (T1D) is of key importance to the effectiveness of the therapy, which, in its complexity, requires a great deal of knowledge, attention, and commitment. Intellectual limitations make it difficult to achieve the optimal metabolic balance, and a lack of this alignment can contribute to the further deterioration of cognitive functions. The aim of this study was to provide a narrative review of the current state of knowledge regarding the influence of diabetes on brain structure and functions during childhood and also to present possible actions to optimize intellectual development in children with T1D. Scopus, PubMed, and Web of Science databases were searched for relevant literature using selected keywords. The results were summarized using a narrative synthesis. Disturbances in glucose metabolism during childhood may have a lasting negative effect on the development of the brain and related cognitive functions. To optimize intellectual development in children with diabetes, it is essential to prevent disorders of the central nervous system by maintaining peri-normal glycemic levels. Based on the performed literature review, it seems necessary to take additional actions, including repeated neuropsychological evaluation with early detection of any cognitive dysfunctions, followed by the development of individual management strategies and the training of appropriate skills, together with complex, multidirectional environmental support.