股骨颈骨折老年患者接受全髋关节置换术和半髋关节置换术的直接医疗费用和住院时间的间断时间序列比较分析:一项真实世界全国数据库研究。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-04-01 Epub Date: 2024-02-26 DOI:10.4055/cios23282
Seung-Hoon Kim, Suk-Yong Jang, Yonghan Cha, Bo-Yeon Kim, Hyo-Jung Lee, Gui-Ok Kim
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引用次数: 0

摘要

研究背景我们的研究旨在分析因股骨颈骨折而接受半髋关节置换术(HA)或全髋关节置换术(THA)的老年患者的术后直接医疗费用和住院时间(LOS),并通过按时间比较两组患者的这些变量来确定THA的适应症:在这项大样本队列比较研究中,我们分析了 2011 年至 2018 年韩国国民健康保险审查和评估服务数据库中的数据。纳入的患者定义为因股骨颈骨折接受 HA 或 THA 治疗的 60 岁或以上老年人。使用最近邻匹配算法对倾向评分进行了1:1风险集匹配,危险成分的最大卡尺为0.01。在间断时间序列比较分析中,时间序列的构建以从时间零点算起的 3 年前后的四分之一为时间单位。在分段回归分析中,我们采用了伽马分布和对数链接函数的广义线性模型:共有 4,246 名接受过 THA 的患者与 4,246 名接受过 HA 的对照组患者进行了配对。虽然术后前 6 个月的直接医疗费用和住院时间在统计学上没有显著差异,但术后 24 个月内,THA 患者的直接医疗费用和住院时间相对于 HA 患者有所减少(P < 0.05)。在亚组分析中,在 65 ≤ 年龄 < 80 岁年龄组中,THA 组术后 7 至 36 个月的住院时间比医管局组明显缩短(P < 0.05)。在男性组中,术后7至24个月期间,THA组的直接医疗费用比HA组明显减少(P<0.05):结论:在对股骨颈骨折的老年患者实施 THA 时,应从医疗费用和医疗利用率的角度考虑患者至少存活 2 年的可能性。此外,对于 80 岁以下健康、活跃的男性股骨颈骨折患者,THA 可能比 HA 更值得推荐。
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Comparative Interrupted Time Series Analysis of Direct Medical Expense and Length of Stay in Elderly Patients with Femoral Neck Fractures Who Underwent Total Hip Arthroplasty and Hemiarthroplasty: A Real World Nationwide Database Study.

Background: The objective of our study was to analyze the postoperative direct medical expenses and hospital lengths of stay (LOS) of elderly patients who had undergone either hemiarthroplasty (HA) or total hip arthroplasty (THA) for femoral neck fractures and to determine the indication of THA by comparing those variables between the 2 groups by time.

Methods: In this comparative large-sample cohort study, we analyzed data from the 2011 to 2018 Korean National Health Insurance Review and Assessment Service database. The included patients were defined as elderly individuals aged 60 years or older who underwent HA or THA for a femoral neck fracture. A 1:1 risk-set matching was performed on the propensity score, using a nearest-neighbor matching algorithm with a maximum caliper of 0.01 of the hazard components. In comparative interrupted time series analysis, time series were constructed using the time unit of one-quarter before and after 3 years from time zero. For the segmented regression analysis, we utilized a generalized linear model with a gamma distribution and logarithmic link function.

Results: A total of 4,246 patients who received THA were matched and included with 4,246 control patients who underwent HA. Although there was no statistically significant difference in direct medical expense and hospital LOS for the first 6 months after surgery, direct medical expenses and hospital LOS in THA were relatively reduced compared to the HA up to 24 months after surgery (p < 0.05). In the subgroup analysis, the THA group's hospital LOS decreased significantly compared to that of the HA group during the 7 to 36 months postoperative period in the 65 ≤ age < 80 age group (p < 0.05). Direct medical expenses of the THA group significantly decreased compared to those of the HA group during the period from 7 to 24 months after surgery in the men group (p < 0.05).

Conclusions: When performing THA in elderly patients with femoral neck fractures, the possibility of survival for at least 2 years should be considered from the perspective of medical expense and medical utilization. Additionally, in healthy and active male femoral neck fracture patients under the age of 80 years, THA may be more recommended than HA.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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