急性细菌性脑膜炎成人患者出现低钠血症的频率。

Mymensingh medical journal : MMJ Pub Date : 2024-04-01
M Rashid, S N Das, M M Hasan, M F H Hera, M M Rana, R Saha
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引用次数: 0

摘要

细菌性脑膜炎是一种危及生命的疾病。细菌性脑膜炎患者容易出现急性低钠血症。在中枢神经系统感染中,低钠血症可能是由于抗利尿激素分泌不当综合征所致。本研究显示了急性细菌性脑膜炎成人患者出现低钠血症的频率。这项横断面研究于 2016 年 2 月至 2016 年 7 月在孟加拉国迈门辛格医学院附属医院内科进行。通过有目的的抽样,共有 50 名患者被纳入本研究。在 50 名急性细菌性脑膜炎患者中,33 人(66%)被诊断为低钠血症状态。33例低钠血症细菌性脑膜炎患者的平均血清钠水平为(130.66±2.95)mmol/L。大多数病例(78.79%)为轻度低钠血症状态(130 mmol/L-135 mmol/L),18.18%为中度低钠血症(125 mmol/L-129 mmol/L)。只有 3.03% 的病例为重度病例(≤124 毫摩尔/升)。结果显示,大量急性细菌性脑膜炎患者患有低钠血症,其中大多数病例为轻度低钠血症。
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Frequency of Hyponatremia in Adults with Acute Bacterial Meningitis.

Bacterial meningitis is a life-threatening disease. Bacterial meningitis patients are prone to develop acute hyponatremia. In the central nervous system infection hyponatremia could be due to the Syndrome of Inappropriate Anti Diuretic Hormone secretion. The frequency of hyponatremia in adults with acute bacterial meningitis patients was seen in this study. This cross-sectional study was conducted in the Internal Medicine Department of Mymensingh Medical College Hospital, Mymensingh, Bangladesh from February 2016 to July 2016. A total of 50 patients were enrolled in this study by purposive sampling. Among 50 acute bacterial meningitis patients, 33 (66%) were diagnosed as hyponatremic state. The mean serum sodium level of 33 hyponatremic bacterial meningitis cases was 130.66±2.95 mmol/L. Most of the cases (78.79%) were mild hyponatremic state (130 mmol/L-135 mmol/L) whereas 18.18% were revealed as moderate hyponatremia (125 mmol/L-129 mmol/L). Only 3.03% of cases were presented as severe cases (≤124 mmol/L). The result revealed that a large number of patients with acute bacterial meningitis were suffering from hyponatremia and in the majority of cases were mildly hyponatremic.

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