PD-L1阳性转移性头颈部鳞状细胞癌患者Zanzalintinib联合Pembrolizumab与Pembrolizumab单药治疗(STELLAR-305):一项双盲、随机、安慰剂对照的 2/3 期研究

N. Saba, K. Harrington, L. Licitra, J. Machiels, M. Huang, F. Xu, P. Patel, R. Haddad
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Zanzalintinib Plus Pembrolizumab Versus Pembrolizumab Alone In Patients with PD-L1 Positive Metastatic Head And Neck Squamous Cell Carcinoma (STELLAR-305): A Double-Blind, Randomized, Placebo-Controlled, Phase 2/3 Study
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FIERCE-HN: A Multicenter, Randomized, Placebo-controlled, Phase 3 Study of ficlatuzumab + cetuximab in pts w/ recurrent or Metastatic (R/M) HPV-negative Head and Neck Squamous Cell Carcinoma (HNSCC) Altered Oral Bacteria Abundance Associated with Disease Specific Survival in Oral Squamous Cell Carcinoma Developing Machine Learning Algorithms Incorporating Patient Reported Outcomes to Predict Disease Progression in Head and Neck Cancers Lenvatinib ± Pembrolizumab Versus Chemotherapy for Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) That Progressed after Platinum and Immunotherapy: The Phase 2 LEAP-009 Study Metabolics Underlying Dynamic Optical Contrast Imaging for Head & Neck Cancer Margin Determination
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