子宫球囊填塞术在产后出血治疗中的应用

D. Artymuk, S. Apresyan
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In most cases, postpartum haemorrhage occurs due to atony and is controlled by administration of uterotonics. However, if uncurbed, postpartum haemorrhage requires blood transfusion and surgery. Currently, uterine balloon tamponade is considered as one of the most efficient and safe technologies for controlling postpartum haemorrhage and preventing hysterectomy, yet a number of studies have reported negative results. Several investigations showed an advantage of double-balloon tamponade as it provides an additional benefit of vascular compression of the lower uterine segment. Generally, uterine balloon tamponade is an efficient intervention which allows to avoid additional surgeries (uterine artery embolization or hysterectomy) in 87.3 – 100.0% of cases with a relatively low complication rate (< 6.7% – 9.4%).Conclusion. 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摘要

目的评估子宫球囊填塞治疗产后出血的有效性和安全性。我们在 Cochrane 图书馆和 PubMed 上筛选了以下关键词:"宫腔内球囊填塞"、"可控球囊填塞"、"可控球囊填塞 "和 "产后出血/大出血"。我们共发现了 358 篇出版物,包括 3 篇荟萃分析、6 篇系统综述和 13 篇随机对照试验。在检查标题和摘要以去除重复内容后,我们选择了 38 篇符合选择标准的资料。无论在发展中国家还是发达国家,产后出血仍是孕产妇死亡的主要原因。在大多数情况下,产后出血是由于子宫收缩引起的,并通过使用子宫收缩剂得到控制。但是,如果不加以控制,产后出血就需要输血和手术。目前,子宫球囊填塞术被认为是控制产后大出血和预防子宫切除术的最有效、最安全的技术之一,但也有一些研究报告了负面结果。有几项研究表明,双球囊填塞法的优势在于它能为子宫下段的血管压迫提供额外的益处。一般来说,子宫球囊填塞术是一种有效的干预措施,在 87.3% - 100.0% 的病例中可以避免额外的手术(子宫动脉栓塞或子宫切除术),并发症发生率相对较低(< 6.7% - 9.4%)。子宫球囊填塞术的效果和并发症风险可能取决于设备的类型、学习曲线效应以及医务人员培训的规律性和质量。在这方面还需要进行更深入的多中心研究。
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Uterine Balloon Tamponade in Management of Postpartum Hemorrhage
Aim. To evaluate the efficacy and safety of uterine balloon tamponade for the management of postpartum haemorrhage.Materials and Methods. We have screened the Cochrane Library and PubMed for the following keywords: “intrauterine balloon tamponade”, “controlled balloon tamponade”, “controlled balloon tamponade” AND “postpartum bleeding/haemorrhage” during 5 years (2018-2023). In total, we have identified 358 publications including 3 meta-analyses, 6 systematic reviews, and 13 randomized controlled trials. After checking titles and abstracts to remove duplicates, we selected 38 sources which met the selection criteria.Results. Postpartum haemorrhage remains the leading cause of maternal mortality in both developing and developed countries. In most cases, postpartum haemorrhage occurs due to atony and is controlled by administration of uterotonics. However, if uncurbed, postpartum haemorrhage requires blood transfusion and surgery. Currently, uterine balloon tamponade is considered as one of the most efficient and safe technologies for controlling postpartum haemorrhage and preventing hysterectomy, yet a number of studies have reported negative results. Several investigations showed an advantage of double-balloon tamponade as it provides an additional benefit of vascular compression of the lower uterine segment. Generally, uterine balloon tamponade is an efficient intervention which allows to avoid additional surgeries (uterine artery embolization or hysterectomy) in 87.3 – 100.0% of cases with a relatively low complication rate (< 6.7% – 9.4%).Conclusion. The effectiveness of uterine balloon tamponade and the risk of complications are probably determined by the type of device, the learning curve effect, and the regularity and quality of training of medical personnel. Further in-depth multicenter studies in this direction are required.
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