2023 年 5 月至 7 月期间在亚丁糖尿病中心就诊的 2 型糖尿病患者中的维生素 D:描述性研究

Anis Z. Kahtan, Samira A. Mahmood
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Vitamin D status was categorized as deficient, insufficient, or sufficient based on established cutoffs. Descriptive statistics and chi-square tests were used for data analysis. Results: Majority of patients had vitamin D deficiencyy (73.2%) and the remaining had insufficient (17.4%), and sufficient (9.4%) status. Males comprised 53.6% and females 46.4%. Mean age was 53.70±12.93 years, with the highest proportion (60.9%) were in the age group 40-60 years. Majority of the patients (62.3%) had T2DM duration ≥ 5 years, and 89.1% were receiving diabetes medications, and 68.8% had a family history of DM. The mean RBS level was 220.13±86.90 mg/dl, with more than half (55.6%) having RBS levels ≥ 140 mg/dl. Also, the mean BMI was 27.00±5.90 kg/m², and more than half of the patients had overweight and obesity. 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摘要

导言维生素 D 在 2 型糖尿病(T2DM)的发病和治疗过程中起着至关重要的作用。然而,有关在医疗中心就诊的 T2DM 患者(尤其是也门亚丁糖尿病中心的患者)维生素 D 状况的数据却很有限。本研究旨在评估 T2DM 患者中维生素 D 缺乏症的患病率,并探讨其与人口统计学、糖尿病特征体重指数 (BMI) 等潜在因素的关系。研究方法对 2023 年 5 月至 7 月期间在亚丁糖尿病中心(ADC)就诊的 138 名 T2DM 患者进行了描述性横断面研究。研究人员测量了年龄、性别、糖尿病特征(糖尿病病程、糖尿病家族史和用药情况)、RBS、BMI 和血清维生素 D 水平等数据。根据既定的临界值,维生素 D 状态被分为缺乏、不足或充足。数据分析采用了描述性统计和卡方检验。结果大多数患者维生素 D 缺乏(73.2%),其余为不足(17.4%)和充足(9.4%)。男性占 53.6%,女性占 46.4%。平均年龄为(53.70±12.93)岁,其中 40-60 岁年龄段的比例最高(60.9%)。大多数患者(62.3%)的 T2DM 病程≥ 5 年,89.1%的患者正在接受糖尿病药物治疗,68.8%的患者有糖尿病家族史。平均 RBS 水平为 220.13±86.90 mg/dl,超过半数(55.6%)患者的 RBS 水平≥ 140 mg/dl。此外,平均体重指数(BMI)为 27.00±5.90 kg/m²,半数以上患者超重和肥胖。研究发现,血清维生素 D 水平与年龄、糖尿病特征或 BMI 类别无明显关联,但与性别有明显关联(P = 0.006)。结论这项研究表明,在亚丁 ADC 就诊的 T2DM 患者中,维生素 D 缺乏症的发病率很高。研究发现,大多数患者的维生素 D 水平不足,而年龄、糖尿病特征和体重指数之间的差异有限。维生素 D 水平与性别之间存在明显关联,这表明性别可能导致 T2DM 患者缺乏维生素 D 的风险。这些发现强调了评估和解决 T2DM 患者维生素 D 状态以优化其整体健康和糖尿病管理的重要性。
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Vitamin D Among Type 2 Diabetic Patients Attending Aden Diabetic Center During May-July 2023: A Descriptive Study
Introduction: Vitamin D plays a crucial role in the pathogenesis and management of type 2 diabetes mellitus (T2DM). However, limited data are available regarding the status of vitamin D among T2DM patients attending healthcare centers, particularly in the Aden Diabetic Center, Yemen. The study aimed to assess the prevalence of vitamin D deficiency among T2DM patients and explore its association with potential factors such as demographics, diabetes characteristics body mass index (BMI). Methods: A descriptive cross-sectional study was conducted on 138 T2DM patients attending Aden Diabetic Center (ADC) between May and July 2023. Data on age, sex, diabetes characteristics (diabetes duration, family history of diabetes, and medication use), RBS, BMI, and serum vitamin D level were measured. Vitamin D status was categorized as deficient, insufficient, or sufficient based on established cutoffs. Descriptive statistics and chi-square tests were used for data analysis. Results: Majority of patients had vitamin D deficiencyy (73.2%) and the remaining had insufficient (17.4%), and sufficient (9.4%) status. Males comprised 53.6% and females 46.4%. Mean age was 53.70±12.93 years, with the highest proportion (60.9%) were in the age group 40-60 years. Majority of the patients (62.3%) had T2DM duration ≥ 5 years, and 89.1% were receiving diabetes medications, and 68.8% had a family history of DM. The mean RBS level was 220.13±86.90 mg/dl, with more than half (55.6%) having RBS levels ≥ 140 mg/dl. Also, the mean BMI was 27.00±5.90 kg/m², and more than half of the patients had overweight and obesity. The study found no significant association between serum vitamin D levels with age, diabetes characteristics, or BMI categories, while a significant association to sex was observed (P = 0.006). Conclusion: The study highlights the high prevalence of vitamin D deficiency among T2DM patients attending the ADC in Aden. The majority of patients were found to have deficient levels of vitamin D, with limited differences based on age, diabetes characteristics, and BMI. The significant association between vitamin D levels and sex, indicating that sex may contribute to the risk of deficiency in T2DM patients. These findings emphasize the importance of assessing and addressing vitamin D status in T2DM patients to optimize their overall health and diabetes management.
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