{"title":"具有抗耐甲氧西林金黄色葡萄球菌(MRSA)特性的聚二甲基硅氧烷(PDMS)纳米结构薄膜的制作工艺","authors":"N. L. M. Shamsuddin, K. Mohamed","doi":"10.15251/djnb.2024.191.325","DOIUrl":null,"url":null,"abstract":"Physical topography modification is an approach to fabricate nanostructures surfaces with antimicrobial properties. Lithography-based technologies offer an effective technique to develop the desired sizes and geometry. The replica molding technique was employed to fabricate the PDMS nanostructures using the PMMA imaging layer and characterized using a FESEM and AFM. The cell viability of gram-positive bacteria on structural diminished by almost 80% and the cells were deformed and ruptured once attached to the structured surface. Thus, the PDMS structured surface enhanced the bactericidal properties of the film, which effectively inhibit bacterial attachment.","PeriodicalId":11233,"journal":{"name":"Digest Journal of Nanomaterials and Biostructures","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The fabrication process of polydimethylsiloxane (PDMS) nanostructured films with antimicrobial properties against methicillin-resistant staphylococcus aureus (MRSA)\",\"authors\":\"N. L. M. Shamsuddin, K. Mohamed\",\"doi\":\"10.15251/djnb.2024.191.325\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Physical topography modification is an approach to fabricate nanostructures surfaces with antimicrobial properties. Lithography-based technologies offer an effective technique to develop the desired sizes and geometry. The replica molding technique was employed to fabricate the PDMS nanostructures using the PMMA imaging layer and characterized using a FESEM and AFM. The cell viability of gram-positive bacteria on structural diminished by almost 80% and the cells were deformed and ruptured once attached to the structured surface. Thus, the PDMS structured surface enhanced the bactericidal properties of the film, which effectively inhibit bacterial attachment.\",\"PeriodicalId\":11233,\"journal\":{\"name\":\"Digest Journal of Nanomaterials and Biostructures\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Digest Journal of Nanomaterials and Biostructures\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.15251/djnb.2024.191.325\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Digest Journal of Nanomaterials and Biostructures","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.15251/djnb.2024.191.325","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
The fabrication process of polydimethylsiloxane (PDMS) nanostructured films with antimicrobial properties against methicillin-resistant staphylococcus aureus (MRSA)
Physical topography modification is an approach to fabricate nanostructures surfaces with antimicrobial properties. Lithography-based technologies offer an effective technique to develop the desired sizes and geometry. The replica molding technique was employed to fabricate the PDMS nanostructures using the PMMA imaging layer and characterized using a FESEM and AFM. The cell viability of gram-positive bacteria on structural diminished by almost 80% and the cells were deformed and ruptured once attached to the structured surface. Thus, the PDMS structured surface enhanced the bactericidal properties of the film, which effectively inhibit bacterial attachment.