(O-25) 慢性睾丸疼痛的手术治疗:系统综述

F. C. de Freitas, M. R. Sanches, AdC Dosatti
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引用次数: 0

摘要

慢性睾丸疼痛(CTP)的定义是间歇性或持续性睾丸疼痛长达 3 个月,并对患者造成严重困扰。CTP 有多种不同的手术治疗方案。对于顽固性病例,它们通常被作为二线甚至三线治疗方案。本研究旨在回顾和阐明有关慢性睾丸疼痛手术治疗的文献。 我们在 Pubmed、Embase 和 Cochrane 中检索了评估 CTP 手术治疗的文章。搜索关键词包括 "睾丸痛"、"精索"、"慢性阴囊痛"、"慢性睾丸痛 "和 "手术"。 对于保守疗法无效的特发性慢性睾丸痛,精索神经显微手术(MDSC)是手术标准。精索阻断术的阳性反应是 MDSC 反应的预测指标。MDSC 术后疼痛缓解率从 76% 到 100% 不等。超声引导下靶向冷冻消融术可用于 MDSC 后的顽固性 CTP,成功率为 75%。表皮切除术更适用于囊肿、肉芽肿或肿块等结构异常的 CTP,疼痛缓解率可达 50%至 92%。对于输精管结扎术后疼痛综合征,输精管结扎逆转术和MDSC的总体成功率分别为50%至100%和71%至81%。髂腹股沟和股生殖周围神经刺激可用于顽固性 CTP,脊髓刺激也可用于顽固性 CTP。睾丸切除术可作为最后的选择,以防患者对其他治疗方式无反应,但又不能100%缓解疼痛。 尽管存在多种选择,但目前还没有治疗 CTP 的金标准手术疗法,这对临床医生来说是一个挑战。必须进行大规模的对照试验,才能为 CTP 的手术治疗提供有力、可靠的证据。 无冲突。
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(O-25) SURGICAL TREATMENT FOR CHRONIC TESTICULAR PAIN: A SYSTEMATIC REVIEW
Chronic testicular pain (CTP) is defined as 3 months of intermittent or constant testicular pain that is significantly bothersome to the patient. There exist a variety of different surgical treatment options for CTP. They are generally kept as second or even third-line option for persistent cases. This study aims to review and elucidate the literature about surgical treatment for chronic testicular pain. We searched Pubmed, Embase and Cochrane for articles evaluating surgical treatments for CTP. Search terms included “orchialgia”, “spermatic cord”, “chronic scrotal pain”, “chronic testicular pain” and “surgery”. Microsurgical Denervation of the Spermatic Cord (MDSC) is the surgical standard when a procedure is indicated for idiopathic chronic orchialgia unresponsive to conservative therapies. The positive response to spermatic cord block is a predictor of MDSC response. Pain relief after MDSC ranges from 76% to 100%. Ultrasound-guided targeted cryoablation could be used in persistent CTP after MDSC with 75% success rate. Epididymectomy is better indicated for CTP in structural abnormality such as cyst, granuloma or mass, with pain relief reaching 50% to 92%. In case of post-vasectomy pain syndrome, vasectomy reversal and MDSC has an overall success from 50% to 100% and 71% to 81% respectively. Ilioinguinal and genitofemoral peripheral nerve stimulation could be used in persistant CTP, and spinal cord stimulation as well. Orchiectomy can be considered as a last resort in case patients do not respond to other forms of treatment, but do not delivers a 100% relief a pain. Although it’s variables choices, there is not a gold standard surgical treatment for CTP, representing a challenge for clinicians. Large, controlled trials must be performed to establish strong and reliable evidence for the surgical treatment of CTP. No conflict.
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