评估马钱子和三叶青的抗炎活性

Vaz Carolina Ferreira, Mariano Alan Fernandes, Fracasso Júlia Amanda Rodrigues, Ramos Marcus Vinicius Vieitas, dos Santos Lucineia, Dias Herbert Júnior
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摘要

炎症是人体抵御潜在威胁的一种自然反应,可以通过体育锻炼、适当营养和使用草药(即药用植物)来减轻。在这项研究中,我们旨在研究两种常用药用植物--马钱子和三叶青的挥发性和乙醇馏分的抗炎作用。精油是通过对植物鲜叶进行水蒸馏获得的,而乙醇提取物则是通过传统方法获得的。对所有馏分进行了抗炎活性测试,评估它们稳定红细胞膜、抑制扩散和巨噬细胞吞噬的能力,浓度为 200 至 600 µg mL-1 不等。实验结果表明,与阳性对照组相比,B. trimera 的乙醇部分显示出良好的效果。因此,我们的研究为有关围绕营养使用草药的专业文献做出了贡献,为今后有关这些馏分的研究提供了指导。
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Evaluation of the Anti-inflammatory Activity of Equisetum arvense and Baccharis trimera Fractions
Inflammation is a natural response of the body to defend itself against potential threats and can be reduced through physical activity, proper nutrition, and the use of herbal medicines, which are medicinal plants. In the study, we aim to examine the anti-inflammatory effects of the volatile and ethanolic fractions of two commonly used medicinal plants, Equisetum arvense, and Baccharis trimera. The essential oils were obtained by hydrodistillation of the fresh leaves of the plants, while the ethanolic extracts were obtained using classical methodologies. All fractions were tested for anti-inflammatory activity, evaluating their ability to stabilize the red blood cell membrane and inhibit the spreading, and phagocytosis by macrophages, at concentrations varying from 200 to 600 µg mL-1. The results of the experiments suggest that the ethanolic fraction of B. trimera shows promising results compared to the positive controls. Our investigations thus contribute to the specialized literature on the use of herbal medicines around nutrition, providing guidance for future studies on these fractions.
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