预测心肌梗死幸存者睡眠时间过短风险的提名图

Jun Xu, Gang Qin
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摘要

背景:有关心肌梗塞(MI)后失眠,尤其是心肌梗塞后睡眠时间短的研究仍然有限。目前,还没有现成的指南或风险预测模型来帮助医生管理或预防心肌梗塞后睡眠时间短或失眠。本研究旨在开发一种预测心肌梗死后睡眠时间短风险的提名图。方法:我们利用美国国家健康与营养调查(NHANES)数据库中 2007 年至 2018 年的数据,对 1434 名 20 岁及以上的心肌梗死幸存者进行了回顾性研究。其中,710 名患者被分配到训练组,707 名患者被分配到测试组。我们利用逻辑回归、最小绝对收缩和选择算子(LASSO)回归以及弹性网络进行变量选择。预测模型的稳定性和准确性通过接收器运算特征(ROC)和校准曲线进行评估。结果:我们在提名图中加入了五个变量:年龄、贫困收入比(PIR)、体重指数(BMI)、种族和抑郁。训练组的 ROC 曲线值为 0.636,测试组的 ROC 曲线值为 0.657,通过校准曲线测试证明了该模型具有良好的预测准确性和稳健性。结论 :我们的提名图能有效预测心肌梗死幸存者睡眠时间短的可能性,为临床医生预防和管理心肌梗死后睡眠时间短提供了宝贵的支持。
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Nomogram for Predicting the Risk of Short Sleep Duration in Myocardial Infarction Survivors
Background : Research on post-infarction insomnia, particularly short sleep duration following myocardial infarction (MI), remains limited. Currently, there are no existing guidelines or risk prediction models to assist physicians in managing or preventing short sleep duration or insomnia following MI. This study aims to develop a nomogram for predicting the risk of short sleep duration after MI. Methods : We conducted a retrospective study on 1434 MI survivors aged 20 and above, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database spanning from 2007 to 2018. Among them, 710 patients were assigned to the training group, while 707 patients were allocated to the testing group. We utilized logistic regression, least absolute shrinkage and selection operator (LASSO) regression, and the elastic network for variable selection. The stability and accuracy of the prediction model were assessed using receiver operator characteristics (ROCs) and calibration curves. Results : We included five variables in the nomogram: age, poverty income ratio (PIR), body mass index (BMI), race, and depression. The ROC curves yielded values of 0.636 for the training group and 0.657 for the testing group, demonstrating the model’s good prediction accuracy and robustness through a calibration curve test. Conclusions : Our nomogram can effectively predict the likelihood of short sleep duration in MI survivors, providing valuable support for clinicians in preventing and managing post-MI short sleep duration.
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