持续气道正压治疗妊娠期阻塞性睡眠呼吸暂停的效果:系统回顾

R. Nugent, A. Wee, L. Kearney, C. de Costa
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引用次数: 0

摘要

(Aust N Z J Obstet Gynaecol 2023.2023;63(3):290-300)阻塞性睡眠呼吸暂停(OSA)的特点是由于上气道塌陷导致睡眠时呼吸反复暂停,从而导致氧含量降低。约有 10.5% 的孕妇在孕早期患有 OSA,而在足月妊娠时则高达 30%。在怀孕期间,OSA 会增加妊娠高血压、先兆子痫和妊娠糖尿病的风险。患有 OSA 的母亲所生的婴儿出生体重可能较轻,早产和入住新生儿重症监护室的风险也会增加。基线肥胖会增加孕期发生 OSA 的风险,而改变生活方式是标准的治疗方法,但其对产妇预后的影响有限。持续气道正压(CPAP)是一种有效的 OSA 治疗方法,但有关 CPAP 对孕产妇或胎儿预后影响的研究却很少。本系统综述旨在研究使用 CPAP 是否能改善患有或可能患有 OSA 的孕妇的预后。
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The Effectiveness of Continuous Positive Airway Pressure for Treating Obstructive Sleep Apnoea in Pregnancy: A Systematic Review
(Aust N Z J Obstet Gynaecol 2023. 2023;63(3):290–300) Obstructive sleep apnea (OSA) is characterized by recurrent pauses in breathing during sleep due to upper airway collapse, resulting in decreased oxygen levels. OSA affects around 10.5% of parturients during early pregnancy and up to 30% at term. In pregnancy, OSA is associated with an increased risk for gestational hypertension, pre-eclampsia, and gestational diabetes. Infants born to mothers with OSA may have a lower birth weight and are at increased risk for premature delivery and neonatal intensive care unit admission. Baseline obesity increases the risk of OSA during pregnancy, with lifestyle modifications being the standard treatment, though their influence on maternal outcomes is limited. Continuous positive airway pressure (CPAP) is an effective OSA treatment; however, little research exists on the impact of CPAP on either maternal or fetal outcomes. This systematic review sought to investigate if the use of CPAP improved outcomes for pregnant women with or at risk of OSA.
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