M. Ghazizadeh, M. Mohseni, Mahboobe Asadi, Aref Hoseini
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Mucormycosis Following COVID-19: A Comprehensive Case Series Investigation
Background: Mucormycosis, commonly referred to as 'black fungus,' has arisen as a complication associated with COVID-19. Objectives: This research investigated the clinical features, demographic profiles, and outcomes of patients with mucormycosis during the COVID-19 pandemic. Methods: A case series involving 29 patients diagnosed with mucormycosis was conducted. The study systematically examined demographic information, underlying health conditions, COVID-19 status, and clinical outcomes of these patients. Results: The majority of patients, accounting for 90%, developed mucormycosis subsequent to COVID-19 infection, with diabetes mellitus being the predominant comorbidity, affecting 38% of cases. A higher incidence was observed in males, and the mortality rate was significant. Functional endoscopic sinus surgery (FESS) was utilized for both diagnosis and treatment, although the success rate of this procedure varied. Conclusions: Post-COVID-19 mucormycosis presents intricate clinical challenges, particularly in patients with comorbidities and weakened immune systems. Prompt diagnosis and a comprehensive, multidisciplinary approach are crucial. Additional research is needed to enhance our comprehension and improve treatment strategies for this daunting infection.
期刊介绍:
Archives of Clinical Infectious Diseases is a peer-reviewed multi-disciplinary medical publication, scheduled to appear quarterly serving as a means for scientific information exchange in the international medical forum. The journal particularly welcomes contributions relevant to the Middle-East region and publishes biomedical experiences and clinical investigations on prevalent infectious diseases in the region as well as analysis of factors that may modulate the incidence, course, and management of infectious diseases and pertinent medical problems in the Middle East.