原发性自发性气胸老年患者在自主呼吸下进行胸腔镜手术对炎症指标和术后并发症的影响

Fangjie Xiao, Yan Xia
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引用次数: 0

摘要

背景:在自主呼吸的胸腔镜手术中,患者可在手术过程中自主呼吸,无需通过气管插管进行机械通气。该技术可有效避免气管插管和机械通气造成的损伤以及肌松药的副作用,从而减少术后并发症,造福患者。本研究旨在探讨胸腔镜手术在老年人原发性自发性气胸(PSP)患者自主呼吸下的应用及其对炎症指标和术后并发症的影响。方法选择 2021 年 6 月至 2022 年 6 月在我院接受胸腔镜手术的 181 例老年 PSP 患者的病历进行回顾性分析。排除15例不符合纳入标准的患者后,根据手术中使用的不同方案,将80例通过喉罩通气进行自主呼吸的患者纳入研究组,86例通过单腔气管插管进行肺通气的患者纳入对照组。比较了两组患者的术前麻醉诱导、手术和住院时间,并分析了两组患者的血流动力学、炎症指数和并发症发生率。结果显示两组患者的恢复时间和住院时间有明显差异(P < 0.001)。与对照组相比,研究组在 T2 阶段平均动脉压明显降低,在 T2 和 T3 阶段心率加快(P < 0.001)。在 T5、T6 和 T7,研究组的白细胞介素-6、白细胞介素-8 和 C 反应蛋白水平明显低于对照组(P < 0.05)。两组术中和术后并发症的发生率无明显差异(P > 0.05)。结论在自主呼吸下进行胸腔镜手术治疗老年 PSP 患者是安全有效的。它能降低炎症因子水平,加快术后康复,具有一定的临床推广价值。
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Effect of Thoracoscopic Surgery under Spontaneous Respiration on Inflammatory Indicators and Postoperative Complications in Elderly Patients with Primary Spontaneous Pneumothorax
Background: In thoracoscopic surgery under spontaneous respiration, patients could breathe spontaneously during surgery without the need for mechanical ventilation via tracheal intubation. This technique can effectively avoid the injuries caused by tracheal intubation and mechanical ventilation and the side effects of muscle relaxants, thus reducing postoperative complications and benefitting patients. This study aims to explore the application of thoracoscopic surgery under spontaneous respiration in the elderly with primary spontaneous pneumothorax (PSP) and its effect on inflammatory indices and postoperative complications. Methods: The medical records of 181 elderly patients with PSP who underwent thoracoscopic surgery in our hospital from June 2021 to June 2022 were chosen for retrospective analysis. After excluding 15 patients who did not meet inclusion criteria, 80 patients receiving spontaneous respiration via laryngeal mask ventilation were included in the study group and 86 patients undergoing pulmonary ventilation via single-lumen tracheal intubation were included in the control group in accordance with the different schemes used in the surgery. Preoperative anaesthesia induction, surgical and hospitalisation times were compared, and the haemodynamics and inflammatory indices and complication incidences of the two groups were analysed. Results: Recovery time and hospitalisation time significantly differed between the two groups (p < 0.001). Compared with the control group, the study group had significantly lower mean arterial pressure at T2 and faster heart rates at T2 and T3 (p < 0.001). At T5, T6 and T7, the levels of interleukin-6, interleukin-8 and C-reactive protein in the study group were significantly lower than those in the control group (p < 0.05). The incidence of intraoperative and postoperative complications did not significantly differ between the two groups (p > 0.05). Conclusion: Thoracoscopic surgery under spontaneous respiration is safe and effective in the treatment of elderly patients with PSP. It reduces the levels of inflammatory factors and accelerates postoperative rehabilitation, showing certain value for clinical promotion.
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