交感和副交感中枢自律神经网络

G. Valenza, Francesco Di Ciò, Nicola Toschi, Riccardo Barbieri
{"title":"交感和副交感中枢自律神经网络","authors":"G. Valenza, Francesco Di Ciò, Nicola Toschi, Riccardo Barbieri","doi":"10.1162/imag_a_00094","DOIUrl":null,"url":null,"abstract":"Abstract The central-autonomic network (CAN) comprises brain regions that are functionally linked to the activity of peripheral autonomic nerves. While parasympathetic CAN (i.e., the CAN projecting onto parasympathetic branches) has recently been investigated and is known to be involved in neurological and neuropsychiatric disorders, sympathetic CAN (i.e., the CAN projecting onto sympathetic nerves) has not been fully characterized. Using functional magnetic resonance imaging (fMRI) data from the Human Connectome Project in conjunction with heartbeat dynamics and its orthonormal autoregressive descriptors as a proxy for sympathetic activity estimation, namely, the sympathetic activity index (SAI), we uncover brain regions belonging to the sympathetic CAN at rest. We uncover a widespread CAN comprising both cortical (in all lobes) and subcortical areas, including the cerebellum and brainstem, which is functionally linked to sympathetic activity and overlaps with brain regions driving parasympathetic activity. These findings may constitute fundamental knowledge linking brain and bodily dynamics, including the link between neurological and psychiatric disorders and autonomic dysfunctions.","PeriodicalId":507939,"journal":{"name":"Imaging Neuroscience","volume":"588 2","pages":"1-17"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sympathetic and parasympathetic central autonomic networks\",\"authors\":\"G. Valenza, Francesco Di Ciò, Nicola Toschi, Riccardo Barbieri\",\"doi\":\"10.1162/imag_a_00094\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract The central-autonomic network (CAN) comprises brain regions that are functionally linked to the activity of peripheral autonomic nerves. While parasympathetic CAN (i.e., the CAN projecting onto parasympathetic branches) has recently been investigated and is known to be involved in neurological and neuropsychiatric disorders, sympathetic CAN (i.e., the CAN projecting onto sympathetic nerves) has not been fully characterized. Using functional magnetic resonance imaging (fMRI) data from the Human Connectome Project in conjunction with heartbeat dynamics and its orthonormal autoregressive descriptors as a proxy for sympathetic activity estimation, namely, the sympathetic activity index (SAI), we uncover brain regions belonging to the sympathetic CAN at rest. We uncover a widespread CAN comprising both cortical (in all lobes) and subcortical areas, including the cerebellum and brainstem, which is functionally linked to sympathetic activity and overlaps with brain regions driving parasympathetic activity. These findings may constitute fundamental knowledge linking brain and bodily dynamics, including the link between neurological and psychiatric disorders and autonomic dysfunctions.\",\"PeriodicalId\":507939,\"journal\":{\"name\":\"Imaging Neuroscience\",\"volume\":\"588 2\",\"pages\":\"1-17\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Imaging Neuroscience\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1162/imag_a_00094\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Imaging Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1162/imag_a_00094","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

摘要 中枢自主神经网络(CAN)由与外周自主神经活动有功能联系的脑区组成。近来对副交感神经网络(即投射到副交感神经分支上的网络)进行了研究,发现它与神经和神经精神疾病有关,而交感神经网络(即投射到交感神经上的网络)的特征尚未完全确定。利用人类连接组计划的功能性磁共振成像(fMRI)数据,结合心跳动态及其正交自回归描述符作为交感神经活动估计的替代指标,即交感神经活动指数(SAI),我们发现了属于交感神经CAN的静态脑区。我们发现了一个广泛的交感神经活动区域,包括皮层(所有脑叶)和皮层下区域,其中包括小脑和脑干,它在功能上与交感神经活动相关,并与驱动副交感神经活动的脑区重叠。这些发现可能构成连接大脑和身体动态的基础知识,包括神经和精神疾病与自律神经功能失调之间的联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Sympathetic and parasympathetic central autonomic networks
Abstract The central-autonomic network (CAN) comprises brain regions that are functionally linked to the activity of peripheral autonomic nerves. While parasympathetic CAN (i.e., the CAN projecting onto parasympathetic branches) has recently been investigated and is known to be involved in neurological and neuropsychiatric disorders, sympathetic CAN (i.e., the CAN projecting onto sympathetic nerves) has not been fully characterized. Using functional magnetic resonance imaging (fMRI) data from the Human Connectome Project in conjunction with heartbeat dynamics and its orthonormal autoregressive descriptors as a proxy for sympathetic activity estimation, namely, the sympathetic activity index (SAI), we uncover brain regions belonging to the sympathetic CAN at rest. We uncover a widespread CAN comprising both cortical (in all lobes) and subcortical areas, including the cerebellum and brainstem, which is functionally linked to sympathetic activity and overlaps with brain regions driving parasympathetic activity. These findings may constitute fundamental knowledge linking brain and bodily dynamics, including the link between neurological and psychiatric disorders and autonomic dysfunctions.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Optimization and validation of multi-echo, multi-contrast SAGE acquisition in fMRI BOLD fMRI responses to amplitude-modulated sounds across age in adult listeners Developmental trajectories of the default mode, frontoparietal, and salience networks from the third trimester through the newborn period GABA levels decline with age: A longitudinal study Unveiling hidden sources of dynamic functional connectome through a novel regularized blind source separation approach
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1