COVID-19 是否影响了急性冠状动脉疾病的地区死亡率?(2017-2019年和2020-2022年两个时期的比较)

I. Samorodskaya, M. Bubnova, O. A. Akulova
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引用次数: 0

摘要

目的与流行前(2017-2019 年)相比,评估 2020-2022 年冠状病毒病 2019(COVID-19)大流行期间俄罗斯各地区急性冠状动脉疾病(CAD)死亡率的变化。俄罗斯国家统计局(Rosstat)使用了 82 个俄罗斯地区一岁年龄组的年均人口和死亡率数据。在俄罗斯国家统计局的死因命名简表中,《国际疾病分类》第 10 次修订版(ICD-10)的代码分组如下:I21.0-9(急性原发性)心肌梗塞(MI)、I22.0-9(复发性心肌梗塞)、I20、I24.1-9(其他类型的急性冠状动脉疾病)、U07.1 和 U07.2(2019 年冠状病毒疾病(COVID-19))。地区平均标准化死亡率(SMR;M±SD)采用欧洲人口标准,以每十万人口为单位,使用直接标准化方法计算得出。比较采用非参数 Wilcoxon t 检验(P<0.05 为差异显著)。与大流行前相比,大流行期间的地区平均 SMR(每 10 万人)有所下降:所有急性 CAD 类型的总和从 51,24±31,98 降至 50,21±33,38,重复心肌梗死从 7,65±5,42 降至 4,80±4,84;急性心肌梗死的 SMR 从 24,00±10,1 升至 25,57±11,55,其他急性 CAD 类型的 SMR 从 19,58±25,23 升至 19,83±26,21。三种急性 CAD 类型的 SMR 动态变化以及最小和最大 SMR 都存在显著的地区差异。与大流行前相比,只有两个地区在大流行期间三种急性心血管疾病的每种类型的 SMR 都有所增加。在 18 个地区,三种类型的 SMR 均有所下降,其余地区则出现了多向变化。COVID-19的SMR与急性CAD的SMR之间没有相关性(r=0,034;p=0,76)。COVID-19大流行对急性CAD的地区平均SMR没有显著影响。复发性心肌梗死的SMR大幅下降可能是由于选择了最初的死亡原因。
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Has COVID-19 affected regional mortality from acute coronary artery disease? (comparison of two periods of 2017-2019 and 2020-2022)
Aim. To assess the changes of mortality from acute coronary artery disease (CAD) in the Russian regions during the coronavirus disease 2019 (COVID-19) pandemic in 2020-2022 in comparison with the prepandemic period (2017-2019).Material and methods. Rosstat data on the average annual population and mortality rate in one-year age groups for 82 regions Russian were used. In the brief Nomenclature of Causes of Death of Rosstat, the codes of the International Classification of Diseases, 10th revision (ICD-10) are grouped as follows: I21.0-9 (acute primary) myocardial infarction (MI), I22.0-9 (recurrent MI), I20, I24.1-9 (other types of acute coronary artery disease), U07.1 and U07.2 (coronavirus disease 2019 (COVID-19)). The regional average standardized mortality rates (SMR; M±SD) were calculated using the European population standard using the direct standardization method per 100 thousand population. Comparisons were made using the nonparametric Wilcoxon t-test (differences were considered significant at p<0,05).Results. A decrease in the regional average SMR (per 100 thousand population) in the pandemic compared to the pre-pandemic period was revealed: from the sum of all acute CAD types — from 51,24±31,98 to 50,21±33,38 and from repeated MI — from 7,65±5,42 to 4,80±4,84; increase in SMR from acute MI — from 24,00±10,1 to 25,57±11,55, from other acute CAD types — from 19,58±25,23 to 19,83±26,21. Significant regional variability was noted in both the dynamics of the SMR from three acute CAD types, as well as the minimum and maximum SMR. Only in 2 regions in the pandemic period there was an increase in SMR from each of the three acute CAD types compared to the pre-pandemic period. In 18 regions, there was a decrease in SMR from each of the three forms, and in the rest, multidirectional changes were noted. There was no correlation between SMR for COVID-19 and SMR for acute CAD (r=0,034; p=0,76).Conclusion. The COVID-19 pandemic did not have a significant impact on the regional average SMR from acute CAD. The significant decrease in SMR from recurrent MI is likely due to choice of the initial cause of death.
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来源期刊
Cardiovascular Therapy and Prevention
Cardiovascular Therapy and Prevention Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.70
自引率
0.00%
发文量
155
审稿时长
6-12 weeks
期刊介绍: The most important objectives of the journal are: the generalization of scientific and practical achievements in the field of cardiology, increasing scientific and practical skills of cardiologists. The scientific concept of publication does the publication of modern achievements in the field of epidemiology, prevention and treatment of cardiovascular diseases, the results of research, national and international clinical trials. For publication in the journal are invited both domestic and foreign scientists and clinicians working in the field of cardiology, as well as doctors of other specialties. The magazine covers various issues in cardiology and related specialties. Each issue is prepared by Executive editor of the issue, a respected specialist in the field of epidemiology, prevention and treatment of cardiovascular diseases. The main focus of the publication — scientific articles on original research, the pharmacotherapy of cardiovascular disease, new diagnostic methods. All members of the group of authors should meet all four criteria of authorship set forth in the ICMJE recommendations: 1) concept and design development or data analysis and interpretation, and 2) manuscript justification or verification of critical intellectual content, and 3) final approval for publication of the manuscript, and 4) consent to be responsible for all aspects of the work, and assume that issues relating to the thoroughness and diligent execution of any part of the study submitted are duly investigated and resolved. Great importance the editors attached to the preparation of scientific papers by groups of authors at a high level, literacy, authors, and their ownership information, availability of research results not only to colleagues in Russia, but also abroad.
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