与健康儿童相比，特应性皮炎患儿的未成年期

IF 1.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL Turkish Journal of Medical Sciences Pub Date : 2024-01-01 DOI:10.55730/1300-0144.5795

S. Koca, Hatice Eke Güngör, Murat Cansever

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引用次数: 0

摘要

)水平较高（分别为 p = 0.023、p < 0.001、p = 0.038 和 p = 0.034）。在患有AD的男孩中，FT4水平较低（p = 0.023）。在所有比较中，血清 FT4 和促甲状腺激素水平均在正常参考范围内。结论与对照组相比，患有 AD 的女孩在青春期的雌二醇和 IGF-1 水平下降。在逻辑回归模型中，血清雌二醇、硫酸脱氢表雄酮、FT4和IGF-1水平的降低以及IGFBP3水平的升高与特应性皮炎患病几率的增加有关。

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Minipuberty period of children with atopic dermatitis compared to healthy children

) levels were found to be higher (p = 0.023, p < 0.001, p = 0.038, and p = 0.034, respectively). In boys with AD, the FT4 level was found to be lower (p = 0.023). Serum FT4 and TSH levels were within normal reference ranges in all comparisons. Conclusion: Especially in girls with AD, decreased estradiol and IGF-1 levels were observed compared to the controls during minipuberty. In the logistic regression model, decreased levels of serum estradiol, dehydroepiandrosterone sulfate, FT4, and IGF-1, and increased levels of IGFBP3 were associated with an increased likelihood of exhibiting atopic dermatitis.

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来源期刊

Turkish Journal of Medical Sciences 医学-医学：内科

CiteScore

4.60

自引率

4.30%

发文量

143

审稿时长

3-8 weeks

期刊介绍： Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical details of a given medical subspeciality may not be evaluated for publication.