第 2023 届骨髓脂肪协会夏季学校会议摘要--第 2023 届骨髓脂肪协会夏季学校会议

Biagio Palmisano, Michaela Tencerova
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引用次数: 0

摘要

脂肪是成人骨髓的主要成分,构成所谓的骨髓脂肪组织(BMAT)。骨髓脂肪细胞是骨髓中的脂肪细胞,随着年龄的增长,其数量会越来越多,并可能影响全身的新陈代谢。在骨质疏松症患者中,骨髓脂肪组织的数量与骨量成反比。神经性厌食症患者在外周脂肪组织减少后体重下降,骨髓脂肪细胞会扩大。虽然骨髓脂肪细胞越来越多地被认为是治疗的靶点,但关于它们在骨骼稳态、新陈代谢、癌症和再生治疗中的作用,仍有许多知识需要学习。骨髓脂肪学会(BMAS)成立于 2017 年,旨在加强人们对骨髓脂肪细胞与骨骼健康、癌症和全身代谢之间关系的了解。BMAS 致力于培养年轻科学家,并组织了第二届 BMAS 暑期班,该暑期班将于 2023 年 9 月 4-6 日以虚拟活动的形式举办。
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Abstracts BMAS Summer School 2023—2nd Bone Marrow Adiposity Society Summer School Meeting 2023
Fat is the main component of an adult bone marrow and constitutes the so-called bone marrow adipose tissue (BMAT). Marrow adipocytes, which are the fat cells in the bone marrow, become more abundant with age, and may influence the whole-body metabolism. In osteoporotic patients, the amount of BMAT has an inverse correlation with the amount of bone mass. In people with anorexia nervosa that lose weight after the reduction of peripheral adipose tissues, BMAT expands. Although bone marrow adipocytes are increasingly recognized as a target for therapy, there is still much to learn about their role in skeletal homeostasis, metabolism, cancer, and regenerative treatments. The Bone Marrow Adiposity Society (BMAS), established in 2017, aims to enhance the understanding of how BMAT relates to bone health, cancer, and systemic metabolism. BMAS is committed to training young scientists and organized the second edition of the BMAS Summer School, held on September 4–6, 2023, as a virtual event.
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