症状性腰椎管狭窄症患者选择手术与不选择手术的倾向匹配研究

IF 1.9 Q3 CLINICAL NEUROLOGY Brain & spine Pub Date : 2024-01-01 DOI:10.1016/j.bas.2024.102802
Casper Friis Pedersen , Søren Eiskjær , Mikkel Østerheden Andersen , Leah Yacat Carreon , Peter Doering
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引用次数: 0

摘要

引言尽管大多数治疗腰椎管狭窄症(LSS)患者的外科医生都认为手术治疗优于保守治疗,但系统学回顾得出的结论是没有确凿证据支持这一观点。研究问题比较转诊至脊柱外科诊所并选择手术治疗和未选择手术治疗的无症状 LSS 患者 1 年后在行走能力、健康相关生活质量、腿痛和背痛方面的变化。未接受手术的患者与从丹麦国家脊柱登记处检索到的队列进行了倾向匹配。在人口统计学和基线结果测量方面进行了匹配。结果不到一半的非手术患者在EQ-5D-3L、VAS腿部疼痛或VAS背部疼痛方面达到了MCID,而2/3的手术患者达到了MCID。差异最大的是 VAS 背痛,27.5% 的非手术组患者达到了 12 分的 MCID,而手术组为 71.8%。然而,还需要进一步的研究来比较手术减压和非手术治疗对 LSS 患者的效果。
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A propensity-matched study of patients with symptomatic lumbar spinal stenosis opting for surgery versus not

Introduction

Although most surgeons treating patients with lumbar spinal stenosis (LSS) believe that surgical treatment is superior to conservative measures, systematics reviews have concluded that no solid evidence support this.

Research question

To compare change at 1-year of walking ability, health-related quality of life, leg and back pain in patients with symptomatic LSS referred to a spine surgery clinic who opted for surgery and those who did not.

Material and methods

The study included 149 operated and 149 non-operated patients seen by spine surgeons and diagnosed with LSS. The non-operated patients were propensity-matched to a cohort retrieved from the Danish national spine registry. Matching was done on demographics and baseline outcome measures. The outcomes was walking improvement measured by item 4 of the Oswestry Disability Index, EQ-5D-3L, global assessment (GA) of back/leg pain, back and leg pain on the Visual Analogue Scale and the Short Form 36 transition item 2.

Results

Less than half of the non-operated reached MCID on EQ-5D-3L, VAS pain legs or VAS pain back where 2/3 of the operated did. The largest difference was VAS back pain where 27.5% of the non-operated reached an MCID of 12 points compared to 71.8% in the operated group.

Discussion and conclusion

Surgical treated patients improved better than non-operated on all outcome measures. However, further research is required to compare the effectiveness of surgical decompression with non-operative care for LSS patients.

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来源期刊
Brain & spine
Brain & spine Surgery
CiteScore
1.10
自引率
0.00%
发文量
0
审稿时长
71 days
期刊最新文献
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