新改良的 "假瓣 "在不损害血管的情况下加强了长输尿管远端缺损的修复:前瞻性数据库的回顾性分析

IF 1.6 Q3 UROLOGY & NEPHROLOGY BJUI compass Pub Date : 2024-02-20 DOI:10.1002/bco2.327
Majid Mirzazadeh, Merhan Badran, Whitney Smith
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引用次数: 0

摘要

目的 介绍一种用于重建长输尿管缺损的替代技术--假皮瓣,以替代 Boari 皮瓣。尽管泌尿科医生使用 Boari 皮瓣无张力重建输尿管远端和中段缺损已有 70 多年的历史,但其并发症发生率很高,平均为 27%(5.5%-30.4%)。造成这些并发症的原因是皮瓣三面都有切口,且皮瓣基底是唯一的供血来源,因此供血受到影响。 方法 我们对 2008 年至 2021 年期间由一位外科医生采用改良技术进行手术的患者进行了回顾性分析。在完全解除粘连并在必要时牺牲上膀胱蒂后,我们在膀胱前部和对侧最低处进行了半斜膀胱切开术。该技术的创新部分是在假瓣两侧不同位置做短的松弛切口,同时将膀胱穹隆向上推,以无张力的方式到达健康的输尿管,然后用无回流或回流技术进行吻合。 结果 15名患者接受了假瓣技术,平均随访时间为16.9个月。其中四名患者曾接受过放射治疗,三名患者曾因腹膜癌变接受过腹腔内热化疗(HIPEC),一名患者的移植肾出现输尿管狭窄。术中会诊时进行了八项手术。 只有一名患者(7%)出现了重大并发症(Clavien-Dindo ≥2级)。这名患者出现了术后渗漏,没有人出现梗阻性肾积水,提示有狭窄或皮瓣缺血。皮瓣的平均长度为 9.3 厘米。 结论 与传统的 Boari 皮瓣相比,我们的假瓣技术并发症发生率较低。它没有技术难度,对血液供应的影响最小,因此特别适用于组织血管减少的复杂、高发病率患者,如曾接受过放射治疗和腹膜癌变的患者。
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Newly modified ‘pseudo flap’ without compromising vascularity to enhance repair of long distal ureteral loss: A retrospective analysis of a prospective database

Objective

To present an alternative technique called pseudo-flap for reconstructing long ureteral defects as an alternative to Boari flap. Despite being used for more than 70 years by urologists for tension-free reconstruction of distal and mid-ureteral defects, the Boari flap exhibits high complication rates, with an average of 27% (range 5.5%–30.4%). These complications arise from compromised blood supply, attributed to incisions made on all three sides of the flap and dependence on the flap base as the sole source of blood supply.

Methods

We retrospectively reviewed patients who underwent our modified technique by a single surgeon between 2008 and 2021. We used a semi-oblique cystotomy on the lowest part of the anterior and contralateral aspects of the bladder after complete release from adhesions and sacrificing the superior vesical pedicle, if necessary. The innovative part of the technique involved making short relaxing incisions at different levels on both sides of a pseudo-flap while pushing the bladder dome upward to reach the healthy ureter in a tension-free manner, followed by anastomosis with a non-refluxing or refluxing technique.

Results

Fifteen patients underwent the pseudo-flap technique with a mean follow-up of 16.9 months. Four had prior radiation, three had hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis, and one had a ureteral stricture in a transplanted kidney. Eight procedures were performed during intraoperative consultations.

Only one patient (7%) developed a major complication (Clavien–Dindo grade ≥2). This patient developed postoperative leak, and none developed obstructive hydronephrosis, suggesting stricture or flap ischemia. The mean length of the flap was 9.3 cm.

Conclusion

Our pseudo-flap technique has lower complication rates than the traditional Boari flap. It is not technically challenging, minimally compromises blood supply and is thus especially suitable for complex, highly morbid patients with decreased tissue vascularity, such as those with prior radiation and peritoneal carcinomatosis.

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