{"title":"口服 pH 触发的结肠特异性酮洛芬负载微球，用于更好地治疗类风湿性关节炎相关的清晨症状。第一部分：优化、体外和体内表征","authors":"Krishna Sanka, Prabhakar Reddy Veerareddy, Rajeswara Rao Pragada","doi":"10.1080/01932691.2024.2338359","DOIUrl":null,"url":null,"abstract":"The primary goal of this research was to investigate pH-triggered colon-specific ketoprofen-loaded microspheres (C-SKLM) using Eudragit S-100 as a pH-dependent polymer. The formulation was optimize...","PeriodicalId":15574,"journal":{"name":"Journal of Dispersion Science and Technology","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Oral pH triggered colon-specific ketoprofen loaded microspheres for the better management of early morning symptoms associated with rheumatoid arthritis. Part I: Optimization, in-vitro, and ex-vivo characterization\",\"authors\":\"Krishna Sanka, Prabhakar Reddy Veerareddy, Rajeswara Rao Pragada\",\"doi\":\"10.1080/01932691.2024.2338359\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The primary goal of this research was to investigate pH-triggered colon-specific ketoprofen-loaded microspheres (C-SKLM) using Eudragit S-100 as a pH-dependent polymer. The formulation was optimize...\",\"PeriodicalId\":15574,\"journal\":{\"name\":\"Journal of Dispersion Science and Technology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-04-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Dispersion Science and Technology\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/01932691.2024.2338359\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Dispersion Science and Technology","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/01932691.2024.2338359","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Oral pH triggered colon-specific ketoprofen loaded microspheres for the better management of early morning symptoms associated with rheumatoid arthritis. Part I: Optimization, in-vitro, and ex-vivo characterization
The primary goal of this research was to investigate pH-triggered colon-specific ketoprofen-loaded microspheres (C-SKLM) using Eudragit S-100 as a pH-dependent polymer. The formulation was optimize...
期刊介绍：
Journal of Dispersion Science and Technology is an international journal covering fundamental and applied aspects of dispersions, emulsions, vesicles, microemulsions, liquid crystals, particle suspensions and sol-gel processes. Fundamental areas that are covered include new surfactants, polymers and indigenous stabilizers; surfactant and polymer association as well as phase equilibria in systems water and oil; surfactant and polymer films, monolayers and interfacial films; adsorption and desorption onto solid surfaces; stability and destabilization of dispersions, emulsions and particle suspensions; collodal templates and sol-gel processing. Industrial applications cover chemicals, crude oils, food, pharmaceuticals, agriculture, nanotechnology, and soft condensed materials.
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