贝宁成年人头痛的发病率和与人口统计学的关系:一项基于人口的横断面研究

Thierry Adoukonou, Mendinatou Agbetou, Eric Dettin, Oyene Kossi, Andreas Husøy, Hallie Thomas, Dismand Houinato, Timothy J Steiner
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摘要

全球疾病负担(GBD)研究对头痛疾病的研究越来越深入,但撒哈拉以南非洲地区(SSA)仍然是世界上人口研究直接得出的数据有限的大区之一。全球防治头痛运动在该地区开展了三项研究:东部的埃塞俄比亚、南部的赞比亚和撒哈拉以南非洲中部的喀麦隆。在此,我们报告了在贝宁开展的一项类似研究,这也是首次在西撒哈拉以南非洲地区开展的研究。我们采用了相同的方法和问卷,在该国的三个地区进行了分组随机抽样,在每个地区随机抽取住户,对这些住户进行暗访,并在每个住户中随机抽取一名成年成员(18-65 岁)。HARDSHIP 结构化问卷被翻译成中非法语,由训练有素的访问员进行面对面访问。在进行人口调查后,根据 ICHD-3 标准提出诊断问题。我们从 2550 个有合格成员的家庭中招募了 2400 名参与者(参与比例为 94.1%)。几乎所有参与者(95.2%)都报告了曾经有过头痛,这是终生患病率。74.9%的人报告了去年的头痛情况。经年龄、性别和居住地调整后的 1 年患病率估计值为:所有头痛 72.9%,偏头痛 21.2%(包括明确和可能),TTH 43.1%(也包括明确和可能),可能过度用药(pMOH)4.5%,其他头痛 3.1%,每月≥ 15 天。根据受访前一天的头痛报告,头痛的单日(点)患病率为 14.8%。总体而言,这些结果证明,在贝宁这个低收入国家,头痛疾病非常普遍。pMOH的发病率远高于1%-2%的全球平均水平,这证明贫困并不妨碍药物的过度使用。这项研究的结果与其近邻喀麦隆的一项类似研究的结果基本相同。在偏头痛方面,研究结果与早先在选定的贝宁人群中进行的三项研究中的两项研究结果基本一致,但这些研究并没有考虑可能患有偏头痛的人群。这项研究补充了迄今为止对撒哈拉以南非洲地区头痛的有限了解。
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The prevalence and demographic associations of headache in the adult population of Benin: a cross-sectional population-based study
The Global Burden of Disease (GBD) study is increasingly well informed with regard to headache disorders, but sub-Saharan Africa (SSA) remains one of the large regions of the world with limited data directly derived from population-based studies. The Global Campaign against Headache has conducted three studies in this region: Ethiopia in the east, Zambia in the south and Cameroon in Central SSA. Here we report a similar study in Benin, the first from West SSA. We used the same methods and questionnaire, applying cluster-randomized sampling in three regions of the country, randomly selecting households in each region, visiting these unannounced and randomly selecting one adult member (aged 18–65 years) of each household. The HARDSHIP structured questionnaire, translated into Central African French, was administered face-to-face by trained interviewers. Demographic enquiry was followed by diagnostic questions based on ICHD-3 criteria. From 2,550 households with eligible members, we recruited 2,400 participants (participating proportion 94.1%). Headache ever was reported by almost all (95.2%), this being the lifetime prevalence. Headache in the last year was reported by 74.9%. Age-, gender- and habitation-adjusted estimates of 1-year prevalence were 72.9% for all headache, 21.2% for migraine (including definite and probable), 43.1% for TTH (also including definite and probable), 4.5% for probable medication-overuse (pMOH) and 3.1% for other headache on ≥ 15 days/month. One-day (point) prevalence of headache was 14.8% according to reported headache on the day preceding interview. Overall, these findings are evidence that headache disorders are very common in Benin, a low-income country. The prevalence of pMOH, well above the estimated global mean of 1–2%, is evidence that poverty is not a bar to medication overuse. The findings are very much the same as those in a similar study in its near neighbour, Cameroon. With regard to migraine, they are reasonably in accord with two of three earlier studies in selected Beninese populations, which did not take account of probable migraine. This study adds to the hitherto limited knowledge of headache in SSA.
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