一名患有败血症的早产儿体内的 saopaulonensis 白色念珠菌基因组序列草案

IF 3.6 3区生物学 Q2 MYCOLOGY Mycopathologia Pub Date : 2024-04-15 DOI:10.1007/s11046-024-00838-1

Ya-Ting Ning, Rong-Chen Dai, Zheng-Yu Luo, Meng Xiao, Yingchun Xu, Qun Yan, Li Zhang

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引用次数: 0

摘要

罕见的白色念珠菌（Candida saopaulonensis）从未被报道与人类感染有关。我们报告了从一名患有败血症的早产儿体内分离出的第一例临床分离的 SAOPAULONensis 念珠菌的基因组序列草案。这是该物种首次达到近乎完整的染色体水平并带有结构注释的基因组组装，为探索进化模式和致病基因机制开辟了途径。

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Draft Genome Sequence of Candida saopaulonensis from a Very Premature Infant with Sepsis

The rare fungus Candida saopaulonensis has never been reported to be associated with human infection. We report the draft genome sequence of the first clinical isolate of C. saopaulonensis, which was isolated from a very premature infant with sepsis. This is the first genome assembly reaching the near-complete chromosomal level with structural annotation for this species, opening up avenues for exploring evolutionary patterns and genetic mechanisms of pathogenesis.

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来源期刊

Mycopathologia 生物-真菌学

CiteScore

6.80

自引率

3.60%

发文量

审稿时长

3 months

期刊介绍： Mycopathologia is an official journal of the International Union of Microbiological Societies (IUMS). Mycopathologia was founded in 1938 with the mission to ‘diffuse the understanding of fungal diseases in man and animals among mycologists’. Many of the milestones discoveries in the field of medical mycology have been communicated through the pages of this journal. Mycopathologia covers a diverse, interdisciplinary range of topics that is unique in breadth and depth. The journal publishes peer-reviewed, original articles highlighting important developments concerning medically important fungi and fungal diseases. The journal highlights important developments in fungal systematics and taxonomy, laboratory diagnosis of fungal infections, antifungal drugs, clinical presentation and treatment, and epidemiology of fungal diseases globally. Timely opinion articles, mini-reviews, and other communications are usually invited at the discretion of the editorial board. Unique case reports highlighting unprecedented progress in the diagnosis and treatment of fungal infections, are published in every issue of the journal. MycopathologiaIMAGE is another regular feature for a brief clinical report of potential interest to a mixed audience of physicians and laboratory scientists. MycopathologiaGENOME is designed for the rapid publication of new genomes of human and animal pathogenic fungi using a checklist-based, standardized format.