埃塞俄比亚甘贝拉地区坏疽性口炎的高负担:对来自 "面对非洲 "数据库的坏疽性口炎病例的 12 年回顾性研究

Heron Gezahegn Gebretsadik, Yenigat Abera
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摘要

背景坏疽性口炎是一种传染病,主要影响贫困儿童。本研究利用 "面对非洲 "数据库和 2022 年联合国开发计划署贫困指数报告中的数据,对坏疽性口炎在埃塞俄比亚的流行情况进行了回顾性评估。方法 对 2007 年至 2019 年的医疗记录进行全面审查,共发现 235 例坏疽性口炎病例。采用标准化的数据提取模板系统地收集相关的临床和人口统计学数据,以便进行后续分析。结果 分析显示,估计全国患病率为每10万名高危人群中0.65人,每10万名10岁以下儿童中1.9人。甘贝拉地区的发病率最高(每 100 000 人中有 11.2 人),而本尚古兹地区的发病率最低(每 100 000 人中有 0.25 人)。在≤10 岁的儿童中也观察到类似的模式,甘贝拉和本尚古尔-古穆兹地区的发病率分别为每 10 万人 32.9 例和 0.74 例。结论 该研究强调了坏疽性口炎对埃塞俄比亚尤其是甘贝拉地区 10 岁以下儿童的重大影响。它提供了重要的基线数据,有助于公共卫生专业人员、政策制定者和医疗服务提供者制定循证战略,以防治坏疽性口炎并改善受影响人群的福祉。
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High burden of noma in the Gambella region of Ethiopia: a 12-year retrospective study on noma cases from the Facing Africa database
Background Noma, an infectious disease, mainly affects impoverished children. This study retrospectively assessed noma's prevalence in Ethiopia using data from the Facing Africa database and the 2022 United Nations Development Programme poverty index report. Methods A thorough review of medical records spanning 2007 to 2019 identified a total of 235 noma cases. A standardized data extraction template was employed to systematically gather pertinent clinical and demographic data for subsequent analysis. Prevalence rates were calculated nationally and regionally for both the general population and children aged ≤10 y. Results The analysis revealed estimated national prevalence rates of 0.65 per 100 000 individuals at risk and 1.9 per 100 000 children aged <10 y at risk. The Gambela region exhibited the highest prevalence rate (11.2 per 100 000), whereas the Benshangul Gumuz region had the lowest (0.25 per 100 000). Similar patterns were observed among children aged ≤10 y, with the Gambela and Benshangul Gumuz regions reporting rates of 32.9 and 0.74 per 100 000, respectively. Conclusions The study highlights noma's significant impact on children aged <10 y in Ethiopia, especially in the Gambella region. It offers crucial baseline data to assist public health professionals, policymakers and healthcare providers in formulating evidence-based strategies to combat noma and improve affected individuals' well-being.
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