血管生成素样蛋白 8 在代谢功能障碍相关性脂肪肝及其进展中的预测价值：病例对照研究

IF 4.2 3区医学 Q1 ENDOCRINOLOGY & METABOLISM World Journal of Diabetes Pub Date : 2024-04-09 DOI:10.4239/wjd.v15.i3.418

Lu-Lu Gan, Can Xia, Xuan Zhu, Yue Gao, Wen-Chang Wu, Qi Li, Ling Li, Zhe Dai, Yi-Min Yan

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引用次数: 0

摘要

代谢功能障碍相关性脂肪肝（MAFLD）的发病率正在迅速上升，目前约占全球人口的 25%。肝纤维化是脂肪肝发展的关键阶段，晚期肝纤维化会增加肝硬化和肝细胞癌的风险。与更复杂的标志物相比，简单的血清标志物在诊断肝纤维化方面效果较差。然而，由于设备和技术的限制，瞬态弹性成像等成像技术在临床应用中面临着局限性。因此，当务之急是找到一种简单而有效的方法来评估 MAFLD 相关的肝纤维化。

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Predictive value of angiopoietin-like protein 8 in metabolic dysfunction-associated fatty liver disease and its progression: A case-control study.

The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is rapidly increasing, currently affecting approximately 25% of the global population. Liver fibrosis represents a crucial stage in the development of MAFLD, with advanced liver fibrosis elevating the risks of cirrhosis and hepatocellular carcinoma. Simple serum markers are less effective in diagnosing liver fibrosis compared to more complex markers. However, imaging techniques like transient elastography face limitations in clinical application due to equipment and technical constraints. Consequently, it is imperative to identify a straightforward yet effective method for assessing MAFLD-associated liver fibrosis.

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来源期刊

World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

自引率

2.40%

发文量

909

期刊介绍： The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.