腹股沟疝和切口疝修补术后使用阿片类药物的预测因素

Do Hyun Yun, Margaret A. Plymale, Douglas R. Oyler, Svetla S. Slavova, Daniel L. Davenport, John Scott Roth
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引用次数: 0

摘要

背景每两名腹股沟和切口疝修补术(VIHR)患者中就有一人在术前一年内有术前阿片类药物处方。本研究旨在调查有无术前阿片类药物处方的患者术后处方用量增加的风险因素。方法 回顾了 2013 年至 2017 年的 VIHR 病例。州处方药监测计划数据与患者记录相链接。主要终点是出院后第 45 天的阿片类药物累计配药剂量。使用吗啡毫克当量(MME)进行统一比较。结果205名患者被纳入研究(平均年龄53.5岁;50.7%为女性)。超过 35% 的患者符合术前使用阿片类药物的标准。术前阿片类药物耐受性、表皮伤口感染、目前的吸烟状况以及入院 45 天内的任何阿片类药物配发是术后阿片类药物使用量增加的独立预测因素(p < 0.001)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Predictors of postoperative opioid use in ventral and incisional hernia repair

Background

One in two ventral and incisional hernia repair (VIHR) patients have preoperative opioid prescription within a year before procedure. The study's aim was to investigate risk factors of increased postoperative prescription filling in patients with or without preoperative opioid prescription.

Methods

VIHR cases from 2013 to 2017 were reviewed. State prescription drug monitoring program data were linked to patient records. The primary endpoint was cumulative opioid dose dispensed through post-discharge day 45. Morphine milligram equivalent (MME) was used for uniform comparison.

Results

205 patients were included in the study (average age 53.5 years; 50.7% female). Over 35% met criteria for preoperative opioid use. Preoperative opioid tolerance, superficial wound infection, current smoking status, and any dispensed opioids within 45 days of admission were independent predictors for increased postoperative opioid utilization (p < 0.001).

Conclusion

Preoperative opioid use during 45-day pre-admission correlated strongly with postoperative prescription filling in VIHR patients, and several independent risk factors were identified.

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