人参素对糖尿病神经病变模型中疼痛标记物和神经元活力的影响

IF 2.5 4区医学 Q3 ENDOCRINOLOGY & METABOLISM Archives of Physiology and Biochemistry Pub Date : 2024-04-10 DOI:10.1080/13813455.2024.2336922

Muhammed Mirac Kelestemur, Ferah Bulut, Batuhan Bılgın, Munevver Gizem Hekım, Muhammed Adam, Sibel Ozcan, Mustafa Caglar Beker, Nalan Kaya Tektemur, Suat Tekin, Sinan Canpolat, Mete Ozcan

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摘要

本研究探讨了慢性人参素（HN）治疗对糖尿病小鼠背根神经节（DRG）疼痛相关标记物（NMDA、P 物质、TRPV1 和 IL-1β）的影响。此外，我们还评估了...

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Humanin’s impact on pain markers and neuronal viability in diabetic neuropathy model

This study investigates the impact of chronic humanin (HN) treatment on pain-related markers (NMDA, substance P, TRPV1, and IL-1β) in diabetic mice’s dorsal root ganglia (DRG). Additionally, we ass...

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来源期刊

Archives of Physiology and Biochemistry ENDOCRINOLOGY & METABOLISM-PHYSIOLOGY

CiteScore

6.90

自引率

3.30%

发文量

期刊介绍： Archives of Physiology and Biochemistry: The Journal of Metabolic Diseases is an international peer-reviewed journal which has been relaunched to meet the increasing demand for integrated publication on molecular, biochemical and cellular aspects of metabolic diseases, as well as clinical and therapeutic strategies for their treatment. It publishes full-length original articles, rapid papers, reviews and mini-reviews on selected topics. It is the overall goal of the journal to disseminate novel approaches to an improved understanding of major metabolic disorders. The scope encompasses all topics related to the molecular and cellular pathophysiology of metabolic diseases like obesity, type 2 diabetes and the metabolic syndrome, and their associated complications. Clinical studies are considered as an integral part of the Journal and should be related to one of the following topics: -Dysregulation of hormone receptors and signal transduction -Contribution of gene variants and gene regulatory processes -Impairment of intermediary metabolism at the cellular level -Secretion and metabolism of peptides and other factors that mediate cellular crosstalk -Therapeutic strategies for managing metabolic diseases Special issues dedicated to topics in the field will be published regularly.