拉丁美洲生物库系统回顾:生物医学研究的优势和局限性

J. Adrián Rivera-Alcántara, Natalia Esparza-Hurtado, Gabriela A. Galán-Ramírez, Ivette Cruz-Bautista, Roopa Mehta, Carlos A. Aguilar-Salinas, Alexandro J. Martagon
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引用次数: 0

摘要

生物库是通过收集生物材料及其相关数据发展和应用科学研究与国际合作的宝贵工具。2022 年末,我们按照《系统综述和元分析首选报告项目》指南在 PubMed 和 Scopus 上进行了系统研究,由于可用数据有限,我们对 17 篇文章进行了深入审查,并使用《批判性评估技能计划检查表》对其进行了批判性评估;此外还纳入了同行评审期刊以外的 12 个相关卫生组织和政府网站。我们的研究确定了拉丁美洲的 44 家生物库。总体而言,目前缺乏保证存储材料质量和机构合作的法规和立法。我们认为需要就生物库的术语和定义达成共识。还应该就知情同意书的设计达成一致,以确保机构间共享数据的隐私性。总之,在拉丁美洲,显然需要政府支持建立生物库的具体程序,并为现有的生物库提供进一步的支持。
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A systematic review of biobanks in Latin America: Strengths and limitations for biomedical research
Biobanks are valuable tools for developing and applying scientific research and international cooperation through the collection of biological materials and their associated data. Systematic research following the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines was conducted in late 2022 in PubMed and Scopus, and generated 17 articles to be reviewed in depth and critically assessed using the Critical Appraisal Skills Programme Checklist due to the limited available data; 12 relevant health organizations and government websites outside of peer-reviewed journals were also included. Our research identified 44 biobanks in Latin America. In general, there is a lack of regulation and legislation guaranteeing the stored materials’ quality and institutional collaboration. We believe a consensus needs to be reached regarding the terminology and definitions used for biobanks. The design for informed consent should also be agreed upon to ensure the privacy of the data shared among institutions. In conclusion, in Latin America, there is a clear need for government support in creating specific procedures for biobanks and providing further support for existing biobanks.
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Human epididymal protein 4 and its combined detection show good diagnostic value in lung cancer: A retrospective study A systematic review of biobanks in Latin America: Strengths and limitations for biomedical research
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