Rania Mostafa A. Hassan, Saeed Abdel Monem Ebrahim, Marwa Rashad Ahmad Kamal, Heba Fathy Ahmad Tantawy
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Based on O-RADS MRI score, 44.4% of masses were diagnosed as O-RADS II indicating that they were almost certainly benign, 11.1% as O-RADS III indicating low risk malignancy, 8.3% as O-RADS IV indicating intermediate risk malignancy and 36.1% were diagnosed as O-RADS V indicating high risk malignancy. O-RADS MRI score for malignancy gave sensitivity of 92.31% (95%CI 63.97–99.81), specificity of 82.61% (95%CI 61.22–95.05), PPV of 75% (95%CI 54.84–88.11) and NPV of 95% (95%CI 74.12–99.21) with an overall accuracy of 86.11% (95%CI 70.50–95.33). The O-RADS MRI score has excellent accuracy and validity in determining whether an AM is malignant or benign. Using this score in clinical practice may enable a tailored, patient-centered approach for masses that are sonographically indeterminate, avoiding unnecessary surgery, and in certain cases allows less extensive surgery, or even fertility preservation when appropriate.","PeriodicalId":11540,"journal":{"name":"Egyptian Journal of Radiology and Nuclear Medicine","volume":"60 1","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The impact of using ovarian-adnexal reporting data system magnetic resonance imaging (O-RADS MRI) score on risk stratification of sonographically indeterminate adnexal masses\",\"authors\":\"Rania Mostafa A. Hassan, Saeed Abdel Monem Ebrahim, Marwa Rashad Ahmad Kamal, Heba Fathy Ahmad Tantawy\",\"doi\":\"10.1186/s43055-024-01252-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Adnexal masses (AMs) are prevalent, leading to a substantial clinical effort including imaging for diagnosis, surgery, and pathology. The goal of this research was to evaluate the reliability of the Ovarian-Adnexal Reporting Data System Magnetic Resonance Imaging (O-RADS MRI) scale for diagnosing the sonographically indeterminate adnexal masses and to discriminate between malignant and benign ones using the O-RADS MRI scoring system. This study included 72 cases with indeterminate adnexal masses in any age group. We excluded patients with previous history of operated adnexal lesion and patients who had contraindications for MRI as pacemakers or iron clips. Based on O-RADS MRI score, 44.4% of masses were diagnosed as O-RADS II indicating that they were almost certainly benign, 11.1% as O-RADS III indicating low risk malignancy, 8.3% as O-RADS IV indicating intermediate risk malignancy and 36.1% were diagnosed as O-RADS V indicating high risk malignancy. O-RADS MRI score for malignancy gave sensitivity of 92.31% (95%CI 63.97–99.81), specificity of 82.61% (95%CI 61.22–95.05), PPV of 75% (95%CI 54.84–88.11) and NPV of 95% (95%CI 74.12–99.21) with an overall accuracy of 86.11% (95%CI 70.50–95.33). The O-RADS MRI score has excellent accuracy and validity in determining whether an AM is malignant or benign. 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引用次数: 0
摘要
附件肿块(AMs)很常见,临床上需要进行大量的工作,包括影像诊断、手术和病理检查。本研究的目的是评估卵巢-附件报告数据系统磁共振成像(O-RADS MRI)量表诊断声像图不确定附件肿块的可靠性,并使用 O-RADS MRI 评分系统区分恶性和良性肿块。本研究纳入了 72 例任何年龄段的未确定附件肿块患者。我们排除了既往有附件病变手术史的患者,以及有心脏起搏器或铁夹等磁共振成像禁忌症的患者。根据 O-RADS MRI 评分,44.4% 的肿块被诊断为 O-RADS II 级,表示几乎肯定是良性的;11.1% 被诊断为 O-RADS III 级,表示恶性风险低;8.3% 被诊断为 O-RADS IV 级,表示恶性风险中等;36.1% 被诊断为 O-RADS V 级,表示恶性风险高。恶性肿瘤的 O-RADS MRI 评分敏感性为 92.31%(95%CI 63.97-99.81),特异性为 82.61%(95%CI 61.22-95.05),PPV 为 75%(95%CI 54.84-88.11),NPV 为 95%(95%CI 74.12-99.21),总体准确性为 86.11%(95%CI 70.50-95.33)。O-RADS MRI 评分在确定 AM 是恶性还是良性方面具有极高的准确性和有效性。在临床实践中使用该评分可为声像图无法确定的肿块提供量身定制的、以患者为中心的方法,避免不必要的手术,在某些情况下可减少手术范围,甚至在适当时保留生育能力。
The impact of using ovarian-adnexal reporting data system magnetic resonance imaging (O-RADS MRI) score on risk stratification of sonographically indeterminate adnexal masses
Adnexal masses (AMs) are prevalent, leading to a substantial clinical effort including imaging for diagnosis, surgery, and pathology. The goal of this research was to evaluate the reliability of the Ovarian-Adnexal Reporting Data System Magnetic Resonance Imaging (O-RADS MRI) scale for diagnosing the sonographically indeterminate adnexal masses and to discriminate between malignant and benign ones using the O-RADS MRI scoring system. This study included 72 cases with indeterminate adnexal masses in any age group. We excluded patients with previous history of operated adnexal lesion and patients who had contraindications for MRI as pacemakers or iron clips. Based on O-RADS MRI score, 44.4% of masses were diagnosed as O-RADS II indicating that they were almost certainly benign, 11.1% as O-RADS III indicating low risk malignancy, 8.3% as O-RADS IV indicating intermediate risk malignancy and 36.1% were diagnosed as O-RADS V indicating high risk malignancy. O-RADS MRI score for malignancy gave sensitivity of 92.31% (95%CI 63.97–99.81), specificity of 82.61% (95%CI 61.22–95.05), PPV of 75% (95%CI 54.84–88.11) and NPV of 95% (95%CI 74.12–99.21) with an overall accuracy of 86.11% (95%CI 70.50–95.33). The O-RADS MRI score has excellent accuracy and validity in determining whether an AM is malignant or benign. Using this score in clinical practice may enable a tailored, patient-centered approach for masses that are sonographically indeterminate, avoiding unnecessary surgery, and in certain cases allows less extensive surgery, or even fertility preservation when appropriate.