高甘油三酯血症诱发胰腺炎的治疗性血浆置换病例报告

IF 0.9 4区医学 Indian Journal of Hematology and Blood Transfusion Pub Date : 2024-04-20 DOI:10.1007/s12288-024-01759-1

D. Behera, R. S. Mallhi, J. Philip, R. Basnotra, S. Chand

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摘要

为了证实血浆置换能够快速降低血清 TG 水平，并为评估这种治疗方法的长期效果提供研究机会，我们介绍了一例因高甘油三酯血症诱发胰腺炎（HTGP）而入院的 35 岁女性病例。她在紧急情况下使用 Spectra Optia 无细胞血浆置换系统进行了治疗性血浆置换（TPE）。患者的血清甘油三酯（TG）从 3953 mg/dl 显著降至 291 mg/dl，挽救了生命。在随后的随访中，治疗性血浆置换术后的血清甘油三酯（TG）水平保持稳定，只进行了保守治疗。高甘油三酯血症诱发胰腺炎的治疗性血浆置换在 ASFA 分类中值得升级。

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A Case Report of Therapeutic Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis

To support the evidence of plasma exchange’s ability to rapidly lower serum TG levels and provide upcoming research opportunities for evaluating the long-term effects of this treatment, we present the case of a 35-year-old female who was admitted for Hypertriglyceridemia-induced Pancreatitis (HTGP). She underwent Therapeutic Plasma Exchange (TPE) using Spectra Optia Apheresis System on an emergency basis. The patient had a remarkable reduction of serum Triglycerides (TG) from 3953 to 291 mg/dl, which was life saving. On subsequent follow-up the serum TG levels remained constant post-TPE with conservative treatment only. Therapeutic plasma exchange deserves an upgrade in ASFA categorization for the indication in Hypertriglyceridemia induced Pancreatitis.

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Indian Journal of Hematology and Blood Transfusion Medicine-Hematology

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期刊介绍： Indian Journal of Hematology and Blood Transfusion is a medium for propagating and exchanging ideas within the medical community. It publishes peer-reviewed articles on a variety of aspects of clinical hematology, laboratory hematology and hemato-oncology. The journal exists to encourage scientific investigation in the study of blood in health and in disease; to promote and foster the exchange and diffusion of knowledge relating to blood and blood-forming tissues; and to provide a forum for discussion of hematological subjects on a national scale. The Journal is the official publication of The Indian Society of Hematology & Blood Transfusion.