输血证据概要:血小板减少症患者置入 CVC 前的血小板输注(PACER 试验)

IF 1.5 4区 医学 Q3 HEMATOLOGY Transfusion Medicine Pub Date : 2024-04-18 DOI:10.1111/tme.13040
Asha Aggarwal
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引用次数: 0

摘要

临床问题:在血小板计数为 10-50 × 109/L 的血液科和重症监护室(ICU)患者中,与输注一个单位的血小板相比,在插入中心静脉导管(CVC)前暂停输注血小板是否会增加出血的发生率?研究证据:暂停输注血小板不符合非劣效性标准,而且会导致更多与 CVC 相关的出血。
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Transfusion Evidence Synopsis: Platelet transfusion before CVC placement in patients with thrombocytopenia (PACER trial)

Clinical question:

In haematology and intensive care (ICU) patients with a platelet count of 10–50 × 109/L, does withholding platelet transfusion prior to central venous catheter (CVC) insertion increase the incidence of bleeding in comparison to transfusing one unit of platelets?

Evidence from study:

Withholding platelet transfusion did not meet the criteria for non-inferiority and resulted in more CVC-related bleeding.

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来源期刊
Transfusion Medicine
Transfusion Medicine 医学-血液学
CiteScore
2.70
自引率
0.00%
发文量
96
审稿时长
6-12 weeks
期刊介绍: Transfusion Medicine publishes articles on transfusion medicine in its widest context, including blood transfusion practice (blood procurement, pharmaceutical, clinical, scientific, computing and documentary aspects), immunohaematology, immunogenetics, histocompatibility, medico-legal applications, and related molecular biology and biotechnology. In addition to original articles, which may include brief communications and case reports, the journal contains a regular educational section (based on invited reviews and state-of-the-art reports), technical section (including quality assurance and current practice guidelines), leading articles, letters to the editor, occasional historical articles and signed book reviews. Some lectures from Society meetings that are likely to be of general interest to readers of the Journal may be published at the discretion of the Editor and subject to the availability of space in the Journal.
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