罕见肾脏疾病的进展和结果

IF 28.6 1区 医学 Q1 UROLOGY & NEPHROLOGY Nature Reviews Nephrology Pub Date : 2024-04-26 DOI:10.1038/s41581-024-00844-y
Susan J. Allison
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引用次数: 0

摘要

为了描述英国罕见病患者的肾脏和患者预后,Gale 及其同事分析了 RaDaR 中 27285 名 28 种不同类型罕见肾病患者的数据。在 9.6 年的中位随访期间,RaDaR 参与者的 5 年累计肾衰竭发生率明显高于 281 万名全因性 CKD 患者(28% 对 1%;P <;0.0001),但存活率更高(标准化死亡率为 0.42;95% CI 为 0.32-0.52;P <;0.0001)。尽管肾衰竭和死亡年龄等指标存在很大差异,但研究人员发现,罕见肾病患者的死亡轨迹要快于其他慢性肾脏病患者。"盖尔总结说:"这些信息可能会重新构建监管者、医疗服务提供者和研究人员对慢性肾脏病、罕见病和肾衰竭的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Progression and outcomes of rare kidney diseases
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来源期刊
Nature Reviews Nephrology
Nature Reviews Nephrology 医学-泌尿学与肾脏学
CiteScore
39.00
自引率
1.20%
发文量
127
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Nephrology aims to be the premier source of reviews and commentaries for the scientific communities it serves. It strives to publish authoritative, accessible articles. Articles are enhanced with clearly understandable figures, tables, and other display items. Nature Reviews Nephrology publishes Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements. The content is relevant to nephrologists and basic science researchers. The broad scope of the journal ensures that the work reaches the widest possible audience.
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