关于患有慢性肾病的老年人认知能力衰弱的研究进展。

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-04-25 DOI:10.1159/000538689
Yuqing Yuan, Jing Chang, Qian-Mei Sun
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引用次数: 0

摘要

背景 随着人口老龄化带来的医疗挑战日益严峻,慢性肾脏病(CKD)患者中老年人的比例也在逐年增加。慢性肾脏病患者的虚弱患病率明显高于普通人群,老年患者也是虚弱和认知障碍的高危人群。认知功能虚弱是虚弱的一个重要亚型,是一种由生理因素引起的认知功能障碍综合征,不包括阿尔茨海默病和其他类型的痴呆症。其特点是身体虚弱和认知功能障碍并存。本文对认知虚弱的概念、流行病学、筛查方法、预防和治疗措施以及慢性肾脏病患者认知虚弱的可能发病机制进行了全面综述。
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Research progress on cognitive frailty in Older Adults with chronic kidney disease.
BACKGROUND As the medical challenges posed by the ageing population become increasingly severe, the proportion of older people among patients with chronic kidney disease (CKD) is increasing every year. The prevalence of frailty in patients with CKD is significantly higher than that in the general population, and older patients are also a high-risk group for frailty and cognitive impairment. Cognitive frailty, as an important subtype of frailty, is a syndrome characterised by cognitive dysfunction caused by physiological factors, excluding Alzheimer's disease and other types of dementia. It is characterised by the coexistence of physical frailty and cognitive impairment. Previous studies have mainly focused on cognitive impairment, and there is limited research on cognitive frailty, particularly in older patients with CKD. SUMMARY This article provides a comprehensive review of the concept, epidemiology, screening methods, prevention and treatment measures and possible pathogenesis of cognitive frailty in patients with CKD.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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