不要害怕出血:评估减肥患者实施标准化预防性肝素方案后的术后出血发生率。

Ryan Chin, Robin Berk, D. Tagerman, Xavier Pereira, Patricia Friedmann, Diego Camacho
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引用次数: 0

摘要

背景:在美国,减肥手术是一种经常实施的手术,每年的手术量达 4 万例。接受减肥手术的患者术后血栓形成的风险很高,静脉血栓栓塞(VTE)发生率高达 6.4%。尽管存在这种风险,但目前还没有指南推荐术后预防 VTE,而且这也不是大多数医院的常规做法。减肥手术后的术后出血率仅为 1.5%;然而,出血风险可能会导致人们对更宽松的 VTE 预防措施犹豫不决。方法:这是对一家医院 2019 年和 2021 年减肥手术的回顾性分析。所有接受袖带胃切除术(SG)、Roux-en-Y 胃旁路术(RYGB)或转换为 RYGB 的患者的数据均来自代谢与减肥手术认证和质量改进计划(MBSAQIP)和电子病历审查。主要结果是综合出血事件,包括术后输血、术后内镜检查或返回手术室(因出血)、腹腔内血肿、胃肠道(GI)出血或切口血肿。结果队列中共有2067名患者,其中2019年有1043例手术,2021年有1024例手术。在2021年实施深静脉血栓(DVT)预防方案后,出血事件之间没有差异(27对28起,P = .76)。2019 年和 2021 年的单个出血事件没有差异。此外,2019 年和 2021 年的 VTE 发生率也无明显差异(2 对 5 例,P = .28)。结论:在实施出院后预防性肝素标准方案后,我们没有发现减肥手术患者的出血事件发生率增加。因此,外科医生可以考虑在出院后使用化学药物预防 VTE,而不必担心出血问题。
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Don't Fear the Bleed: Assessing Postoperative Bleeding Incidence After Instituting a Standardized Prophylactic Heparin Protocol in Bariatric Patients.
Background: Bariatric surgery is a frequently performed procedure in the United States, accounting for ∼40,000 procedures annually. Patients undergoing bariatric surgery are at high risk for postoperative thrombosis, with a venous thromboembolism (VTE) rate of up to 6.4%. Despite this risk, there is a lack of guidelines recommending postoperative VTE prophylaxis and it is not routine practice at most hospitals. The postoperative bleeding rate after bariatric surgery is only 1.5%; however, the risk of bleeding may lead to hesitancy for more liberal VTE prophylaxis. Methods: This is a retrospective analysis of bariatric surgeries at a single institution in 2019 and 2021. Data were obtained from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) and electronic medical record review for all patients undergoing sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), or conversion to RYGB. The primary outcomes were composite bleeding events, which included postoperative transfusion, postoperative endoscopy or return to operating room (OR) (for bleeding), intra-abdominal hematoma, gastrointestinal (GI) bleeding, or incisional hematoma. Results: There were a total of 2067 patients in the cohort, with 1043 surgeries in 2019 and 1024 surgeries in 2021. There was no difference between bleeding events after instituting a deep venous thrombosis (DVT) prophylaxis protocol in 2021 (27 versus 28 events, P = .76). There was no difference in individual bleeding events between 2019 and 2021. Additionally, there was no significant difference in the rate of VTE between 2019 and 2021 (2 versus 5 events, P = .28). Conclusions: After instituting a standard protocol of prophylactic heparin postdischarge, we did not find an increased rate of bleeding events in patients undergoing bariatric surgery. Thus, surgeons can consider prescribing postdischarge chemical VTE prophylaxis without concern for bleeding.
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