经导管主动脉瓣置换术治疗二尖瓣主动脉瓣狭窄的研究进展

Liyan Chen, Li Jiang, Mei Zou, Xuanlan Chen, Zhiyong Wu
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摘要

双尖瓣狭窄患者通常具有椭圆形瓣环、瓣膜钙化程度高且不对称、瓣叶不等长、升主动脉和/或横向心脏同时增宽等解剖学特征。这些不利因素更容易导致经导管主动脉瓣置换术(TAVR)瓣膜置放不良、瓣膜支架膨胀不良,从而导致瓣膜耐久性降低、瓣周残留渗漏、瓣环和周围结构破裂,以及升主动脉夹层等严重的手术相关并发症。总之,二尖瓣狭窄的 TAVR 治疗正受到越来越多的关注。在这篇手稿中,我们回顾了经导管主动脉瓣置换术治疗二尖瓣主动脉瓣狭窄的研究进展。
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Research Progress of Transcatheter Aortic Valve Replacement in Aortic Valve Stenosis due to Bicuspid Aortic Valve
Patients with bicuspid stenosis often have anatomical characteristics such as elliptical valve rings, high and asymmetric valve calcification, unequal valve leaflets, and concomitant widening of the ascending aorta and/or transverse heart. These unfavorable factors are more likely to cause poor placement of transcatheter aortic valve replacement (TAVR) valves, poor expansion of valve stents, which can lead to reduced valve durability, residual perivalve leakage, rupture of valve rings and surrounding structures, and serious surgical related complications such as ascending aortic dissection. In summary, TAVR treatment for mitral stenosis is receiving increasing attention. In this manuscript, we reviewed the research progress of transcatheter aortic valve replacement in aortic valve stenosis due to bicuspid aortic valve.
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