芦根(Withania somnifera)--其抗菌和抗癌活性

Aleksandra Mazurkiewicz, Wojciech Mądry, Magdalena Kołodziej, Joanna Męczyńska, Nazarii Saiuk, Michał Andrzej Kozicz, Tomasz Seredyński, Adriana Wojciechowska, Justyna Marcicka, Weronika Salasa
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引用次数: 0

摘要

引言 芦根是一种传统的印度植物,由于其潜在的健康益处,尤其是抗菌和抗癌特性,正日益受到全世界科学家的关注。研究目的 本综述旨在讨论有关睡茄对抗菌效果的影响及其在抗癌治疗中的潜在应用的最新发现。材料与方法:本文基于 Pubmed 和 Google Scholar 数据库撰写。使用关键字对文献进行了综述:Ashwagandha"、"Withania Somnifera"、"抗菌"、"抗癌"、"副作用"、"呼吸系统癌症"。研究结果 研究证实,睡茄具有显著的抗菌和抗癌作用。它能抑制革兰氏阴性菌和革兰氏阳性菌的生长。此外,它还具有抗癌活性,尤其是对乳腺癌,能刺激细胞凋亡,诱导癌细胞产生细胞毒性作用,并提高细胞对辐射的敏感性。结论 尽管研究结果令人鼓舞,但仍有必要对芦荟的益处,尤其是长期益处,进行更深入的研究。人们越来越需要对芦荟在治疗各种疾病(包括癌症和细菌感染)方面的潜在益处进行更多的研究,并开发出更有效的治疗策略。强调需要进行大型随机研究,比较长期临床疗效。
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Ashwagandha (Withania somnifera) - Its Antibacterial and Anticancer Activity
Introduction Ashwagandha, a traditional Indian plant, is gaining increasive attention from scientists worldwide due to its potential health benefits, especially in the context of its antibacterial and anticancer properties. Aim of the study The aim of this review was to discuss recent findings regarding the impact of Withania Somnifera on antibacterial effect and its potential applications in anticancer therapy. Materials and methods: The paper was created based on the Pubmed and Google Scholar database. The literature was reviewed using the keywards: ,,Ashwagandha”, ,,Withania Somnifera”, ,,antibacterial ”, ,,anticancer”, ,,side effects”, ,,breats cancer”. Results Studies have confirmed Withania Somnifera, exhibits significant anticacterial and anticancer effects. It inhibits the growth of both Gram-negative and Gram-positive bacteria. Futhermore, it demonstrates anticancer activity, especially in breast cancer, by stimulating apoptosis, induction of cytotoxic effects on cancerous cells and increasing cell sensitivity to radiation. Conclusion Despite promising results, futher research on the benefits of Ashwagandha, particulary in the long term, is essential. There is growing need of more research of the potencial benefits of Ashwagandha in the treatment of various disorders including cancer and bacterial infections and to develop more effective therapeutic strategies. The need for large randomized studies comparing long term clinical effectiveness is emphasized
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