合成生物学及其在美国医学治疗中的潜力:全面回顾:探索生物学和工程学在药物开发和治疗中的前沿交叉点

Francisca Chibugo Udegbe, Ogochukwu Roseline Ebulue, Charles Chukwudalu Ebulue, Chukwunonso Sylvester Ekesiobi
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摘要

本研究全面回顾了生物学和工程学在医学治疗领域的前沿交叉,重点关注合成生物学的进步和应用。研究的主要目的是探索合成生物学的历史演变、界定其范围并分析当前的先进水平,尤其是在药物开发和治疗策略方面。研究方法采用了系统的文献综述和内容分析,利用一系列学术数据库收集 2013 年至 2023 年间发表的相关同行评审文章。主要研究结果表明,合成生物学通过整合工程原理和生物系统,在医学治疗方面取得了重大创新。这些创新包括开发新型给药系统、靶向疗法和个性化医疗方法。研究强调了当前合成生物学方法所面临的挑战和局限性,如伦理问题、监管障碍以及跨学科合作的必要性。合成生物学在医学领域的未来前景既充满挑战,又充满希望。该领域在解决复杂疾病和改善医疗服务方面具有巨大潜力,但在伦理考虑和监管框架方面面临重大挑战。报告为研究人员、行业领导者和政策制定者提供了战略建议,强调了持续创新、伦理应用和全面监管战略的必要性。最后,合成生物学是医学治疗领域的一股变革力量,具有彻底改变医疗保健的潜力。未来的研究应侧重于克服当前的局限性和探索新的应用,确保该领域不断进步,为全球医疗保健事业做出贡献。关键词合成生物学 医学治疗 药物开发 生物工程
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SYNTHETIC BIOLOGY AND ITS POTENTIAL IN U.S. MEDICAL THERAPEUTICS: A COMPREHENSIVE REVIEW: EXPLORING THE CUTTING-EDGE INTERSECTIONS OF BIOLOGY AND ENGINEERING IN DRUG DEVELOPMENT AND TREATMENTS
This study provides a comprehensive review of the cutting-edge intersections of biology and engineering in the realm of medical therapeutics, focusing on the advancements and applications of synthetic biology. The main objectives were to explore the historical evolution, define the scope, and analyze the current state-of-the-art in synthetic biology, particularly in drug development and treatment strategies. The methodology employed a systematic literature review and content analysis, utilizing a range of academic databases to gather relevant peer-reviewed articles published between 2013 and 2023. Key findings revealED that synthetic biology, through the integration of engineering principles and biological systems, has led to significant innovations in medical therapeutics. These include the development of novel drug delivery systems, targeted therapies, and personalized medicine approaches. The study highlights the challenges and limitations in current synthetic biology approaches, such as ethical concerns, regulatory hurdles, and the need for interdisciplinary collaboration. The future landscape of synthetic biology in medicine is marked by both challenges and prospects. The field holds immense potential for addressing complex diseases and enhancing healthcare delivery, yet faces significant challenges in ethical considerations and regulatory frameworks. Strategic recommendations are provided for researchers, industry leaders, and policymakers, emphasizing the need for continuous innovation, ethical applications, and comprehensive regulatory strategies. Finally, synthetic biology stands as a transformative force in medical therapeutics, with the potential to revolutionize healthcare. Future research should focus on overcoming current limitations and exploring new applications, ensuring the field's continued advancement and contribution to global healthcare. Keywords: Synthetic Biology, Medical Therapeutics, Drug Development, Bioengineering.
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