一名肢端肥大症患者的巨大垂体腺瘤病例

Zahra Ismail, Fatima-Ezzahra Mennani, S. Rafi, G. E. Mghari, N. Ansari
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引用次数: 0

摘要

肢端肥大症的特点是生长激素分泌过多,通常由垂体腺瘤引起,它给诊断和治疗带来了挑战,尤其是在伴有巨大浸润性肿瘤的情况下。我们报告了一例 26 岁男性患者的病例,他患有渐进性视力障碍、头痛和全身症状,显示为肢端肥大症。体格检查显示肢端肥大症的典型特征,同时伴有神经功能缺损。诊断性检查证实了巨大浸润性垂体腺瘤的存在,突出了临床、放射学和生化评估在诊断中的重要性。尽管进行了手术治疗,但残余肿瘤依然存在,因此需要辅助药物治疗。治疗涉及多学科方法,包括手术、药物治疗和可能的放射治疗。该病例强调了治疗伴有巨大腺瘤的肢端肥大症的复杂性,强调了早期识别和个体化治疗策略对优化疗效的重要性。
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A Case of an Incredibly Giant Pituitary Adenoma in an Acromegalic Patient
Acromegaly, characterized by excessive growth hormone secretion often due to pituitary adenomas, presents diagnostic and therapeutic challenges, particularly when associated with giant invasive tumors. We present a case of a 26-year-old male with progressive visual impairment, headaches, and systemic symptoms indicative of acromegaly. Physical examination revealed classic features of acromegaly along with neurological deficits. Diagnostic work-up confirmed the presence of a giant invasive pituitary adenoma, highlighting the importance of clinical, radiological, and biochemical evaluation in diagnosis. Despite surgical intervention, residual tumor remained, necessitating adjunctive medical therapy. Management involved a multidisciplinary approach, incorporating surgery, pharmacotherapy, and potentially radiotherapy. This case underscores the complexities of managing acromegaly with giant adenomas, emphasizing the importance of early recognition and individualized treatment strategies to optimize outcomes.
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