{"title":"具有抗菌活性的吡唑基光引发剂","authors":"Melda Altikatoglu Yapaoz, Sevnur Keskin Dogruyol","doi":"10.14314/polimery.2024.3.3","DOIUrl":null,"url":null,"abstract":"1-(naphthalen-2-yl)-2-(1H-pyrazol-1-yl) ethanone (MPPY) was synthesized. The structure was characterized by spectral analysis (1H-NMR, FTIR). The molar absorptivity of MPPY is high enough, similarly to acetonaphthone derivatives, to be used as an efficient type I photoinitiator. The influence of MPPY concentration and the addition of the co-initiator N-methyldiethanolamine (MDEA) on methyl methacrylate (MMA) polymerization were also investigated. Additionally, MPPY showed good antibacterialactivity against Escherichia coli and Staphylococcus aureus (diffusion method).","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":"28 5","pages":""},"PeriodicalIF":17.7000,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pyrazole-based photoinitiator with antibacterial activity\",\"authors\":\"Melda Altikatoglu Yapaoz, Sevnur Keskin Dogruyol\",\"doi\":\"10.14314/polimery.2024.3.3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"1-(naphthalen-2-yl)-2-(1H-pyrazol-1-yl) ethanone (MPPY) was synthesized. The structure was characterized by spectral analysis (1H-NMR, FTIR). The molar absorptivity of MPPY is high enough, similarly to acetonaphthone derivatives, to be used as an efficient type I photoinitiator. The influence of MPPY concentration and the addition of the co-initiator N-methyldiethanolamine (MDEA) on methyl methacrylate (MMA) polymerization were also investigated. Additionally, MPPY showed good antibacterialactivity against Escherichia coli and Staphylococcus aureus (diffusion method).\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":\"28 5\",\"pages\":\"\"},\"PeriodicalIF\":17.7000,\"publicationDate\":\"2024-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.14314/polimery.2024.3.3\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.14314/polimery.2024.3.3","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
合成了 1-(萘-2-基)-2-(1H-吡唑-1-基)乙酮（MPPY）。通过光谱分析（1H-NMR、FTIR）对其结构进行了表征。MPPY 的摩尔吸收率很高，与萘乙酮衍生物类似，可用作高效的 I 型光引发剂。此外，还研究了 MPPY 浓度和添加辅助引发剂 N-甲基二乙醇胺（MDEA）对甲基丙烯酸甲酯（MMA）聚合的影响。 此外，MPPY 对大肠杆菌和金黄色葡萄球菌具有良好的抗菌活性（扩散法）。
Pyrazole-based photoinitiator with antibacterial activity
1-(naphthalen-2-yl)-2-(1H-pyrazol-1-yl) ethanone (MPPY) was synthesized. The structure was characterized by spectral analysis (1H-NMR, FTIR). The molar absorptivity of MPPY is high enough, similarly to acetonaphthone derivatives, to be used as an efficient type I photoinitiator. The influence of MPPY concentration and the addition of the co-initiator N-methyldiethanolamine (MDEA) on methyl methacrylate (MMA) polymerization were also investigated. Additionally, MPPY showed good antibacterialactivity against Escherichia coli and Staphylococcus aureus (diffusion method).
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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