探索在高危人群中使用暴露前预防疗法 (PrEP) 预防艾滋病毒的有效性

Pallav Dave
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引用次数: 0

摘要

要解决艾滋病毒给全球带来的负担,就必须采取有效的预防措施,这些措施已被证明具有很高的有效率。PrEP 是有效预防艾滋病毒的预防措施之一。不同的临床试验和人群研究表明,PrEP 在预防艾滋病毒方面的有效率为 40% 至 90%。由于疗效高,PrEP 可以减少被认为是高危人群的艾滋病毒新感染病例。然而,要想达到高疗效,就需要提高服药依从性,并解决现有的限制服用的障碍。其中一些障碍包括缺乏知识、获取途径不足、污名化、对服务提供者缺乏信任、对 HIV 风险认识不足、费用以及对副作用的恐惧。消除这些障碍可以提高 PrEP 的使用率,有助于降低高危人群感染 HIV 的风险。为消除这些障碍,可以采取的一些措施包括提供教育和培训、分配足够的资源、利用技术、降低 PrEP 的成本、增加保险覆盖面以及加强目标人群之间的沟通。
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Exploring the Effectiveness of Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention among High-Risk Populations
Addressing the global burden of HIV requires effective preventative measures that have been shown to have high efficacy rates. PrEP is one of the preventative measures that is effective in preventing HIV. Different clinical trials and population studies have shown PrEPto have an efficacy rate of 40% to 90% when it comes to preventing HIV. Due to its high efficacy, PrEPcan reduce new HIV infections populations considered to be high risk. However, for efficacy to be high, there is a need to increase medication adherence and address the existing barriers that limit uptake. Some of these barriers are lack of knowledge, inadequate access, stigma,lack of trust in service providers, low perception of HIV risk, cost, and fear of side effects. Addressing these barriers can increase PrEP uptake and help in reducing HIV’s risk among high-risk populations. Some of the measures that can be put in place to address these barriers are providing education and training, allocating enough resources, leveraging technology, lowering PrEP costs, increasing insurance coverage, and improving communication among the targeted population.  
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