病毒诊断测试在呼吸道感染中的作用:向前迈进。

Raúl Ortíz de Lejarazu, J. Eiros, F. López‐Medrano, Milagros Montes, Alfredo Tagarro, María Tomás
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引用次数: 0

摘要

随着病毒学知识的增加和病毒诊断潜力的提高,人们对早期病毒诊断和潜在的早期治疗在呼吸道感染(RTI)治疗中的作用提出了一些相关的问题。为了进一步了解病毒诊断检测在 RTI 治疗中的作用,我们召集了一个专家小组,讨论病毒诊断检测在流感治疗中的作用。专家小组的目标是确定病原学病毒诊断在临床管理中的合理作用;就今后扩大使用此类检测的可能性提出建议,并确定 RTI 管理中的一些不足之处。分子感染病毒诊断(mIVD)检测应用于所有入院的 RTI 成人患者,以及需要入院或将转诊到其他医院接受更专业治疗的儿科患者。增加 mIVD 的使用不仅能减少抗生素的不当使用,从而降低抗生素微生物的耐药性,还能在病原学病毒治疗有效的情况下改善患者的治疗效果,节约资源需求并改善患者的就医流程。在 RTI 中实施 IVD 检测还具有各种组织优势,但将其推广到临床环境中需要制定成本效益战略并进行预算影响评估。
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The role of viral diagnostic tests in respiratory tract infections: moving forward.
The increased knowledge on virology and the increased potential of their diagnostic has risen several relevant question about the role of an early viral diagnosis and potential early treatment on the management of respiratory tract infections (RTI). In order to further understand the role of viral diagnostic tests in the management of RTI, a panel of experts was convened to discuss about their potential role, beyond what had been agreed in Influenza. The objective of this panel was to define the plausible role of aetiologic viral diagnostic into clinical management; make recommendations on the potential expanded use of such tests in the future and define some gaps in the management of RTI. Molecular Infection Viral Diagnostic (mIVD) tests should be used in all adult patients admitted to Hospital with RTI, and in paediatric patients requiring admission or who would be referred to another hospital for more specialised care. The increased use of mIVD will not only reduce the inappropriate use of antibiotics so reducing the antibiotic microbe resistance, but also will improve the outcome of the patient if an aetiologic viral therapy can be warranted, saving resource requirements and improving patient flows. Implementing IVD testing in RTI has various organizational benefits as well, but expanding its use into clinical settings would need a cost-effectiveness strategy and budget impact assessment.
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