D. Abramov, A. Fedorova, E. Volchkov, N. Myakova, D. M. Konovalov
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Current views on the etiology and pathogenesis of ALK-positive anaplastic large cell lymphoma
ALK-positive anaplastic large cell lymphoma is a mature T-cell lymphoma characterized by translocations that involve the ALK receptor tyrosine kinase coding gene. This illness is known to almost exclusively affect children and young adults. The biology of ALK-positive anaplastic large cell lymphoma is fairly well researched today, with recent studies focusing on the histogenesis of this neoplasm. In this review, we analyze the existing world literature data on the etiology and pathogenesis of this disease.
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