下肢慢性静脉疾病中静脉系统不足与临床表现之间的关系

Hubert J. Mendoza Rojas
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摘要

导言:临床、病因、解剖和病理生理学分类法(CEAP)规范了下肢静脉疾病的表现形式。研究目的研究静脉系统不足与 CEAP 临床分类之间的关联。方法:横断面定量分析进行一项定量、横断面、分析性、相关性研究。抽样采用非概率和便利性抽样。样本量为 71 名患者的 136 个下肢。通过双变量逻辑回归(P<0.05),采用卡方、蒙特卡洛和奇数比(OR)统计检验,置信区间为 95%。结果71.8%的受试者为女性,平均年龄为 66.1 岁。最常见的静脉系统不足是浅静脉系统,占 61.7%。扩张的大隐静脉(GSV)100%存在静脉功能不全。最常见的CEAP临床分级是C2(44.9%);35.1%的C1(毛细血管扩张)病例存在静脉系统不足;50%的C2病例存在大隐静脉功能不全(P=0.227)。浅静脉和深静脉系统的不足与 CEAP 临床分类之间存在关联(p=<0.001)。深静脉系统与严重的下肢慢性静脉疾病有关,OR(6.04),95% CI(1.02-35.73),P=0.047。结论研究表明,浅静脉和深静脉系统功能不全与 CEAP 临床分类之间存在关联。三分之一患有 C1(毛细血管扩张)的下肢静脉系统不足。
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Association between insufficient venous systems and clinical manifestations in chronic venous disease of the lower limbs
Introduction: The clinical, etiological, anatomical, and pathophysiological classification (CEAP) standardizes the manifestations of lower limb venous disease. Objective: To investigate the association between insufficient venous systems and the clinical classification of CEAP. Methods: A quantitative, cross-sectional, analytical, correlational study was conducted. Sampling was non-probabilistic and convenience-based. The sample size was 136 lower limbs from 71 patients. Chi-square, Monte Carlo and Odd ratio (OR) statistical tests were used with 95% confidence intervals through bivariate logistic regression (p<0.05). Results: 71.8% of the subjects were female, with an average age of 66.1 years. The most frequent insufficient venous system was the superficial system, present in 61.7% of cases. 100% of the dilated great saphenous veins (GSV) had insufficiency. The most common CEAP clinical class was C2 (44.9%); 35.1% of C1 (telangiectasia) cases had an insufficient venous system; 50% of C2 cases had GSV insufficiency (p=0.227). There was an association between the insufficiency of both superficial and deep venous systems and the CEAP clinical classification (p=<0.001). The deep venous system was associated with severe chronic venous disease of the lower limbs, OR (6.04) with a 95% CI (1.02-35.73) and p=0.047. Conclusions: The study demonstrated an association between the insufficiency of both superficial and deep venous systems and the CEAP clinical classification. One third of the lower limbs with C1 (telangiectasias) had an insufficient venous system.
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