抗结核药物导致的 DRESS 综合征:一个复杂病例,成功实现了对 A 组药物的再脱敏

C. Morán-Mariños, F. Llanos-Tejada, J. Salas-López, A. Chavez-Huamani, Renato Casanova-Mendoza, Renzo Villanueva-Villegas
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引用次数: 0

摘要

摘要 伴有嗜酸性粒细胞增多和全身症状的药物反应(DRESS)综合征是由某些药物引起的一种罕见的、危及生命的不良反应。临床表现通常包括皮疹、发热、淋巴结肿大和嗜酸性粒细胞增多,在某些病例中还可能累及主要器官。这种由抗结核(TB)药物引起的不良反应会导致治疗中断、依从性下降或治愈失败,从而对公共健康造成威胁。我们为您介绍一位 23 岁的女性患者,她因服用 A 组抗结核药物(ATDs)而出现 DRESS 综合征,这种情况极为罕见。通过重新脱敏方案,患者成功地恢复了用药。
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DRESS syndrome due to anti-TB drugs: A complex case with successful re-desensitization of group A drugs
ABSTRACT Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, life-threatening adverse reaction caused by certain medications. Clinical findings usually include rash, fever, lymphadenopathy, and eosinophilia, and in some cases, they may affect major organs. This reaction caused by antituberculosis (TB) medication poses a public health risk due to treatment discontinuation, adherence, or success in cure. We present a 23-year-old female patient who developed DRESS syndrome as a result of group A anti-TB drugs (ATDs), an exceedingly rare occurrence. The patient’s medication was successfully retrieved using a re-desensitization protocol.
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