抑郁症青少年童年创伤与非自杀性自伤行为之间的关系:反刍的中介作用

Wenxian Fu, Xinyi Li, Sifan Ji, Tingting Yang, Lu Chen, Yaru Guo, Kongliang He
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摘要

非自杀性自伤(NSSI)行为在患有抑郁症的青少年中非常常见,而童年创伤被认为是导致抑郁症恶化的远端风险因素之一。不良创伤经历引起的反思可通过 NSSI 行为转移,从而缓解青少年的抑郁症状。本研究主要关注三者之间的关系,在以往研究的基础上进一步探讨反刍是否是童年创伤与NSSI行为之间关系的中介因素,并为今后对青少年抑郁症患者的早期干预提供一些建议。方法 从国内12家医院共招募了833名符合DSM-5抑郁发作标准的青少年抑郁症患者。采用中文版自残功能评估、童年创伤问卷和反刍量表作为研究工具。结果 NSSI组抑郁症青少年的童年创伤和反刍得分均高于非NSSI组。皮尔逊相关分析表明,童年创伤与反刍呈正相关(r=0.165,P<0.01),不同类型的童年创伤与反刍及其三个因子呈显著正相关,这些结果均有统计学意义。反刍在一定程度上介导了青少年抑郁症患者的童年创伤与 NSSI 行为之间的关系(效应大小=0.002),且女性参与者的效应(效应大小=0.003)大于男性参与者(效应大小=0.002)。结论 童年创伤和反刍是抑郁症青少年 NSSI 行为的关键因素。童年创伤不仅直接影响青少年抑郁症患者的 NSSI 行为,还通过反刍间接影响 NSSI 行为。
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The Relationship Between Childhood Trauma and Non-Suicidal Self-Injury Behavior in Adolescents with Depression: The Mediating Role of Rumination
Objective Non-suicidal self-injury (NSSI) behavior is very common in adolescents with depression, and childhood trauma is considered one of the distal risk factors for its exacerbation. Rumination caused by adverse traumatic experiences, which can be transferred through NSSI behavior, can alleviate symptoms of depression in adolescents. The current research focuses on the relationship between the three, further exploring whether rumination is a mediator in the relationship between childhood trauma and NSSI behavior on the basis of previous studies, and provides some suggestions for future early intervention for adolescents with depression. Methods A total of 833 adolescent patients with depression who met the DSM-5 criteria for depressive episode were recruited from 12 hospitals in China. The Chinese version of the Function Assessment of Self-mutilation, Childhood Trauma Questionnaire, and Rumination Inventory were used as research tools. Results The scores of childhood trauma and rumination in adolescents with depression in the NSSI group were higher than those in the non-NSSI group. A Pearson’s correlation analysis showed that childhood trauma was positively correlated with rumination (r=0.165, P<0.01), different types of childhood trauma were significantly positively correlated with rumination and its three factors, and these results were statistically significant. Rumination partially mediated the relationship between childhood trauma and NSSI behavior in depressed adolescent patients (effect size=0.002), and the effect in female participants (effect size=0.003), was greater than that in male participants (effect size=0.002). Conclusion Childhood trauma and rumination were key factors for NSSI behavior in adolescents with depression. Childhood trauma not only has a direct effect on NSSI behavior in adolescent depression, but also plays an indirect effect on NSSI behavior through rumination.
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