乳腺癌患者同时接受乳房重建保守手术对其生活质量和抑郁情绪的影响

N. Zaher, Emad M. Abdelrahman, Ola Seif, Mohamed F. Abdelfattah, Refaat S. Salama
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引用次数: 0

摘要

背景:乳房切除术会导致中度至重度抑郁和焦虑。研究目的本研究旨在评估乳房保守手术和乳房重建对生活质量(QOL)的影响。患者和方法本次回顾性研究纳入了 62 名接受改良根治性乳房切除术(MRM)或乳房保守手术(BCS)加乳房重建的 T1 和 T2 乳腺癌患者。研究对患者的生活质量、抑郁以及术后并发症进行了评估和比较。研究结果本次研究共纳入 62 名女性患者,A 组和 B 组患者的平均年龄分别为(43.20±4.49)岁和(44.36±5.16)岁。接受 MRM 的患者平均手术时间明显更短(P 值 =0.001)。两组患者的贝氏抑郁量表(BDI)评分均有统计学意义,BCS 组的改善幅度更大。6 个月后,两组患者的心理健康、社交健康和精神健康均有明显改善,其中 A 组改善明显:保守乳房手术加重建为改良根治性乳房切除术提供了一种肿瘤学上安全的替代方案,对 QOL 的影响较小,相关的抑郁也较少。
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The Effect of Concomitant Conservative Breast Surgery with Reconstruction on Quality of Life of and Depression in Breast Cancer Patients
Background: Mastectomy leads to moderate to severe degrees of depression and anxiety. Objectives: This study aimed to evaluate the outcome of breast conservative surgery with breast reconstruction on the quality of life (QOL). Patients & methods: The current retrospective study included 62 patients with T1, and T2 breast cancer who underwent modified radical mastectomy (MRM) or breast conservative surgery (BCS) with reconstruction. Evaluation of the quality of life, depression as well as post-operative complications was reported and compared. Results: The current study included 62 female patients with mean age of 43.20 ± 4.49 and 44.36 ± 5.16 in groups A and B respectively. There was a significantly lower mean operative time (P value =0.001) in patients who underwent MRM. There was statistically significant beck depression inventory (BDI) scores in both groups with more improvement in BCS group. Both groups reported statistically significant improvement of psychological well-being, social well-being, and spiritual well-being after 6 months with significant improvement in group A. Conclusion: Conservative breast surgery with reconstruction offers an oncologically safe alternative for modified radical mastectomy with less impact on the QOL and associated with less depression
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