世卫组织真菌优先病原体清单:审查优先次序的关键性重新评估。

IF 20.9 1区 生物学 Q1 INFECTIOUS DISEASES Lancet Microbe Pub Date : 2024-07-01 DOI:10.1016/S2666-5247(24)00042-9
Giacomo Casalini MD , Andrea Giacomelli MD , Prof Spinello Antinori PhD
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引用次数: 0

摘要

2022 年 10 月,世卫组织公布了第一份真菌优先病原体清单,将 19 种真菌分为三个优先组(关键、高和中等),以确定研究工作的优先次序。最终排名是通过多标准决策分析确定的,同时考虑了研发需求和公共卫生重要性。在本个人观点中,我们讨论了真菌病原体的定位,即粘菌目、念珠菌属、组织胞浆菌属、球孢子菌属和副球孢子菌属、镰刀菌属、真菌瘤致病菌、马拉色菌属和肺孢子菌属,同时对世卫组织真菌优先病原体列表排名与这些病原体相关的实际疾病负担之间的潜在差异表示担忧。最后,我们提出了一份经修订的优先病原体列表,其中也考虑到了真菌疾病负担的地区差异。
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The WHO fungal priority pathogens list: a crucial reappraisal to review the prioritisation

In October, 2022, WHO published the first fungal priority pathogen list, which categorised 19 fungal entities into three priority groups (critical, high, and medium), for prioritisation of research efforts. The final ranking was determined via multiple criteria decision analysis, considering both research and development needs and perceived public health importance. In this Personal View, we discuss the positioning of the fungal pathogens, namely, Mucorales, Candida spp, Histoplasma spp, Coccidioides and Paracoccidioides spp, Fusarium spp, eumycetoma causative agents, Talaromyces marneffei, and Pneumocystis jirovecii, while expressing concerns about potential disparities between the WHO fungal priority pathogen list ranking and the actual disease burden associated with these pathogens. Finally, we propose a revised prioritisation list that also considers the regional disparities in the burden of fungal diseases.

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来源期刊
Lancet Microbe
Lancet Microbe Multiple-
CiteScore
27.20
自引率
0.80%
发文量
278
审稿时长
6 weeks
期刊介绍: The Lancet Microbe is a gold open access journal committed to publishing content relevant to clinical microbiologists worldwide, with a focus on studies that advance clinical understanding, challenge the status quo, and advocate change in health policy.
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