立体定向心律失常射频消融术及其对现代心脏电生理学的影响:EHRA 调查结果

Boldizsar Kovacs, H Immo Lehmann, Martin Manninger, Ardan M Saguner, Piotr Futyma, David Duncker, Julian Chun
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摘要

背景 立体定向心律失常射频消融术(STAR)是治疗结构性心脏病(SHD)患者复发性室速/室颤(VT/VF)的一种方法。心脏病专家对 STAR 目前和未来的作用尚不清楚。目的 评估 STAR 的当前作用、应用障碍和未来预期作用。方法 进行了一项在线调查,调查内容包括 20 个问题,涉及 STAR 的基线人口统计学、认知/获取、当前使用和未来作用。结果 129 名国际参与者完成了调查(平均年龄为 43±11 岁,女性 25 人(16.4%))。91名参与者(59.9%)是电生理学家。九名参与者(7%)不知道 STAR 是一种治疗方法。64人(49.6%)有机会使用 STAR,62人(48.1%)曾治疗或转介病人接受治疗。STAR 的常见主要适应症是 SHD 复发 VT/VF(45%)、无 SHD 复发 VT/VF (7.8%)或室性早搏(PVC,3.9%)。据报告,STAR 的主要优点是能有效治疗不适合常规治疗的心律失常(49%),以及采用无创治疗方法,预计急性和短期手术风险总体较低(23%)。大多数受访者预计 STAR 将在治疗伴有或不伴有潜在 SHD 的 VT/VF 中发挥临床作用(分别为 72% 和 75%),但只有少数受访者预计 STAR 将成为一线适应症(分别为 7% 和 5%)。结论 STAR 作为复发性 VT 的新型治疗方案似乎已被心脏病学界接受。进一步的试验对于进一步明确疗效、患者人群以及治疗 VT 的适当临床用途至关重要。
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STereotactic Arrhythmia Radioablation and its implications for modern cardiac ElectroPhysiology: Results of an EHRA Survey
Background Stereotactic arrhythmia radioablation (STAR) is a treatment option for recurrent ventricular tachycardia/fibrillation (VT/VF) in patients with structural heart disease (SHD). The current and future role of STAR as viewed by Cardiologists is unknown. Objective To assess the current role, barriers to application and expected future role of STAR. Methods An online survey consisting of 20 questions on baseline demographics, awareness/access, current use, and the future role of STAR was conducted. Results 129 international participants completed the survey (mean age 43±11 years, 25 (16.4%) female). Ninety-one (59.9%) participants were electrophysiologists. Nine participants (7%) were unaware of STAR as a therapeutic option. Sixty-four (49.6%) had access to STAR while 62 (48.1%) had treated/referred a patient for treatment. Common primary indications for STAR were recurrent VT/VF in SHD (45%), recurrent VT/VF without SHD (7.8%) or premature ventricular contraction (PVC, 3.9%). Reported main advantages of STAR were efficacy in the treatment of arrhythmias not amenable to conventional treatment (49%) and noninvasive treatment approach with overall low expected acute and short-term procedural risk (23%). Most respondents have foreseen a future clinical role of STAR in the treatment of VT/VF with or without underlying SHD (72% and 75%, respectively), although only a minority expected a first-line indication for it (7% and 5%, respectively). Conclusions STAR as a novel treatment option of recurrent VT appears to gain acceptance within the cardiology community. Further trials are critical to further define efficacy, patient populations, as well as the appropriate clinical use for the treatment of VT.
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