{"title":"产前使用抗癫痫药物与儿童精神障碍","authors":"BMJ Publishing Group Ltd","doi":"10.1136/dtb.2024.000026","DOIUrl":null,"url":null,"abstract":"### Key learning points A registry-based study has reinforced the need for safety warnings against using valproate during pregnancy because of an increased risk of early-onset developmental disorders in exposed children.1 This prospective cohort study used data on live-born singleton children of mothers with epilepsy from five Nordic countries to examine the association between prenatal use of antiepileptic medication and psychiatric and developmental disorders in exposed offspring.1 Children were followed up from birth until the …","PeriodicalId":11277,"journal":{"name":"Drug and Therapeutics Bulletin","volume":"38 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prenatal use of antiepileptic drugs and childhood psychiatric disorders\",\"authors\":\"BMJ Publishing Group Ltd\",\"doi\":\"10.1136/dtb.2024.000026\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"### Key learning points A registry-based study has reinforced the need for safety warnings against using valproate during pregnancy because of an increased risk of early-onset developmental disorders in exposed children.1 This prospective cohort study used data on live-born singleton children of mothers with epilepsy from five Nordic countries to examine the association between prenatal use of antiepileptic medication and psychiatric and developmental disorders in exposed offspring.1 Children were followed up from birth until the …\",\"PeriodicalId\":11277,\"journal\":{\"name\":\"Drug and Therapeutics Bulletin\",\"volume\":\"38 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Drug and Therapeutics Bulletin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/dtb.2024.000026\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug and Therapeutics Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/dtb.2024.000026","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Prenatal use of antiepileptic drugs and childhood psychiatric disorders
### Key learning points A registry-based study has reinforced the need for safety warnings against using valproate during pregnancy because of an increased risk of early-onset developmental disorders in exposed children.1 This prospective cohort study used data on live-born singleton children of mothers with epilepsy from five Nordic countries to examine the association between prenatal use of antiepileptic medication and psychiatric and developmental disorders in exposed offspring.1 Children were followed up from birth until the …