复杂性憩室乙状结肠炎急诊手术治疗的死亡率,回顾性单中心研究

Corentin Guezennec , Rishika Banydeen , Jean Roudie , Hugo Hertault
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引用次数: 0

摘要

导言乙状结肠憩室炎是指憩室的炎症或感染。它可能是单纯性的,也可能并发脓肿、穿孔、狭窄或瘘管。这些并发症被称为憩室疾病。在出现严重症状时,可能需要采取手术治疗作为紧急措施,或者在后期持续出现致残症状时进行手术治疗。本研究旨在评估急诊处理的复杂乙状结肠憩室炎术后90天的发病率和死亡率。方法我们回顾性地纳入了2010年至2019年期间接受手术治疗的所有复杂乙状结肠憩室炎患者(n = 62)。评估了每位患者的 90 天死亡率。采用 Dindo-Clavien 分级法评估总体发病率,≥III 期为主要发病率。结果 术后 90 天的死亡率为零。根据 Dindo-Clavien 分级,术后 90 天的总发病率为 80.7%,主要发病率为 27.4%。多变量逻辑回归分析显示,男性(OR=6.77[1,40; 32.74],p = 0.02)、体重指数超过 25(OR=58.82[3.95; 876.95],p = 0.01)和吸烟(OR=8.77[0.84; 91.13],p = 0.07)是 90 天后总发病率的独立预测因素。结论在我们的研究中,死亡率为零,总发病率为 80.7%,主要发病率为 27.4%。尽管如此,考虑到急诊手术中吻合口切除的发病率和死亡率没有任何差异,而且经过选择的患者术后恢复消化道连续性的难度较低且更容易,因此手术技术的选择仍有待商榷。
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Morbi-mortality of surgical management in emergency of complicated diverticular sigmoiditis, retrospective monocentric study

Introduction

Sigmoidal diverticulitis is the inflammation or infection of a diverticulum. It may be simple or complicate into an abscess, perforation, stenosis or fistula. These complications are referred to as diverticular disease. Surgical treatment may be required as an emergency measure in the event of serious signs, or at a later stage if disabling symptoms persist. The aim of this study was to assess the 90-day post-operative morbidity and mortality of complicated sigmoidal diverticulitis managed in emergency.

Methods

We retrospectively included all patients (n = 62) with complicated sigmoidal diverticulitis who underwent surgery between 2010 and 2019. 90-day mortality was assessed for each patient. Overall morbidity was assessed using the Dindo-Clavien classification, with major morbidity corresponding to stages ≥III. Factors predictive of overall and major morbidity were analyzed.

Results

Postoperative mortality at 90 days was nil. Overall morbidity at 90 days according to the Dindo-Clavien classification was 80,7 %, with major morbidity at 27,4 %. Multivariate logistic regression analysis retained male gender (OR=6.77[1,40; 32.74], p = 0.02), BMI over 25 (OR=58.82[3.95; 876.95], p = 0.01) and smoking (OR=8.77[0.84; 91.13], p = 0.07) as independent predictors of the occurrence of overall morbidity at 90 days. Likewise, only an ASA score ≥ III was highlighted as an independent predictive factor (OR=5.00[1.51; 16.51], p = 0.01) of major morbidity at 90 days (Dindo-Clavien ≥ III).

Conclusion

In our study, mortality was nil, the overall morbidity rate was 80.7 % and 27.4 % for major morbidity. Nevertheless, the choice of surgical technique remains open to debate, given the absence of any difference in morbidity and mortality from anastomotic resection during emergency surgery, and the less morbid and easier restoration of digestive continuity afterwards in selected patients.

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