从新生儿身上汲取灵感，应对修复成人脊髓的挑战

IF 19.8 1区医学 Q1 CELL & TISSUE ENGINEERING Cell stem cell Pub Date : 2024-05-02 DOI:10.1016/j.stem.2024.04.008

Mickey E. Abraham, Joel Martin, Joseph D. Ciacci

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引用次数: 0

摘要

干细胞疗法已成为一个前景广阔的科学研究领域，尤其在脊髓损伤（SCI）方面引起了广泛关注。Sun 等人1 发现，新生儿脊髓细胞外基质（ECM）可向内源性轴突传递生化信号，从而促进轴突再生。

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Addressing challenges for repairing adult spinal cord with insights from neonates

Stem cell therapy has emerged as a promising area of scientific investigation, sparking considerable interest, especially in spinal cord injury (SCI). Sun et al.¹ discover that the extracellular matrix (ECM) from the neonatal spinal cord transmits biochemical signals to endogenous axons, thus promoting axonal regeneration.

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来源期刊

Cell stem cell 生物-细胞生物学

CiteScore

37.10

自引率

2.50%

发文量

151

审稿时长

42 days

期刊介绍： Cell Stem Cell is a comprehensive journal covering the entire spectrum of stem cell biology. It encompasses various topics, including embryonic stem cells, pluripotency, germline stem cells, tissue-specific stem cells, differentiation, epigenetics, genomics, cancer stem cells, stem cell niches, disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging, therapeutic applications, regenerative medicine, clinical insights, research policies, ethical considerations, and technical innovations. The journal welcomes studies from any model system providing insights into stem cell biology, with a focus on human stem cells. It publishes research reports of significant importance, along with review and analysis articles covering diverse aspects of stem cell research.